ID: ALA2346307
Type: ADME
Description: Metabolic stability in human liver S9 fraction assessed as aldehyde-oxidase-mediated 4-hydroxy-8-(6-methoxypyridin-3-yl)-3-methyl-1-(1-methylpiperidin-4-yl)-1H-imidazo[4,5-c][1,5]naphthyridin-2(3H)-one formation by LC/MS analysis in absence of NADPH
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: S9
Bioactivity
Activity Types for Assay ALA2346307
Stability
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
404.47 | 2.62 | 2.62 |