Basic Information
ID: ALA2346463
Type: Binding
Description: Antagonist activity at P2X7 receptor in human PBMC assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-challenge measured after 1.5 hrs by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2346463
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.64 | 3.93 | 3.93 |
| 488.66 | 4.33 | 4.33 |