Basic Information
ID: ALA2346471
Type: Binding
Description: Inhibition of mouse TDO overexpressed in mouse P815B cells using L-Trp as substrate assessed as kynurenine level at 10 uM by HPLC analysis relative to control
Format: BAO_0000219
Organism: Mus musculus
Cell type: P815B
Target: Tryptophan 2,3-dioxygenase(ALA1075307)
Document: ALA2331397
Inhibition of mouse TDO overexpressed in mouse P815B cells using L-Trp as substrate assessed as kynurenine level at 10 uM by HPLC analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2346471
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.32 | 2.65 | 2.65 |
| 609.70 | 3.70 | 3.70 |
| 609.70 | 3.70 | 3.70 |
| 466.52 | 2.63 | 2.63 |
| 491.57 | 2.56 | 2.56 |
| 491.57 | 2.56 | 2.56 |
| 466.52 | 2.63 | 2.63 |
| 448.50 | 3.06 | 3.06 |
| 489.55 | 3.31 | 3.31 |
| 489.55 | 3.31 | 3.31 |
| 471.54 | 3.98 | 3.98 |
| 448.50 | 3.06 | 3.06 |
| 471.54 | 3.98 | 3.98 |
| 446.48 | 3.81 | 3.81 |
| 292.29 | 2.79 | 2.79 |
| 317.35 | 2.96 | 2.96 |
| 317.35 | 2.96 | 2.96 |
| 292.29 | 2.79 | 2.79 |
| 278.27 | 2.49 | 2.49 |