Assay Report Card

Basic Information

ID: ALA2349934

Type: ADME

Description: Ratio of free drug level in Hartley guinea pig brain at 75 mg/kg, po formulated with 0.5% HPMC/0.5% Tween 80 after 5 hrs to EC50 for BACE1 in HEK293 cells

Tissue: Brain

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
352.412.842.84