Assay Report Card

Basic Information

ID: ALA2350287

Type: Binding

Description: Inhibition of recombinant Plasmodium falciparum plasmepsin 2 expressed in Escherichia coli using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate at 10 uM incubated for 40 mins prior to substrate addition measured after 10 mins by FRET-based fluorometric analysis

Organism: Plasmodium falciparum

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
399.325.255.25
431.955.415.41
567.536.586.58
652.777.987.98
403.514.964.96