Basic Information
ID: ALA2350652
Type: Binding
Description: Competitive inhibition of human recombinant DOT1L (1 to 416 amino acid residues) using [3H]-SAM assessed as inhibition of nucleosome methylation incubated for 30 mins prior to substrate addition measured after 120 mins
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2350652
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.68 | 2.85 | 2.85 |