Basic Information
ID: ALA2352015
Type: Binding
Description: Inhibition of BACE1 in HEK293 cells expressing wild type APP assessed as level of amyloid beta (1 to 40) after 48 hrs by HTRF assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2352015
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.89 | 3.75 | 3.75 |
| 325.39 | 3.40 | 3.40 |
| 325.39 | 3.40 | 3.40 |
| 308.39 | 2.66 | 2.66 |
| 370.84 | 2.95 | 2.95 |
| 358.45 | 3.18 | 3.18 |
| 352.41 | 2.84 | 2.84 |
| 335.41 | 2.10 | 2.10 |
| 308.39 | 2.66 | 2.66 |
| 403.91 | 4.40 | 4.40 |
| 385.87 | 4.10 | 4.10 |
| 376.49 | 3.48 | 3.48 |
| 358.45 | 3.18 | 3.18 |
| 352.41 | 2.84 | 2.84 |
| 386.91 | 3.66 | 3.66 |
| 368.87 | 3.36 | 3.36 |
| 353.45 | 2.40 | 2.40 |
| 335.41 | 2.10 | 2.10 |
| 349.39 | 1.74 | 1.74 |
| 371.39 | 2.65 | 2.65 |
| 383.88 | 3.94 | 3.94 |
| 437.85 | 4.48 | 4.48 |
| 413.91 | 3.57 | 3.57 |
| 495.02 | 4.18 | 4.18 |
| 341.84 | 3.91 | 3.91 |
| 357.91 | 4.63 | 4.63 |
| 371.94 | 5.02 | 5.02 |
| 387.84 | 3.69 | 3.69 |
| 387.84 | 3.69 | 3.69 |
| 393.49 | 3.68 | 3.68 |
| 379.46 | 3.30 | 3.30 |
| 403.40 | 3.92 | 3.92 |
| 381.50 | 3.62 | 3.62 |
| 401.41 | 3.50 | 3.50 |
| 353.40 | 3.04 | 3.04 |
| 341.46 | 3.28 | 3.28 |
| 331.42 | 2.26 | 2.26 |
| 342.44 | 2.22 | 2.22 |
| 336.40 | 2.29 | 2.29 |
| 336.40 | 2.29 | 2.29 |
| 336.40 | 2.29 | 2.29 |
| 370.84 | 2.95 | 2.95 |
| 404.39 | 3.31 | 3.31 |
| 374.44 | 2.66 | 2.66 |
| 354.39 | 2.43 | 2.43 |
| 354.39 | 2.43 | 2.43 |
| 337.38 | 1.69 | 1.69 |
| 342.42 | 2.35 | 2.35 |
| 382.42 | 2.38 | 2.38 |
| 338.20 | 1.99 | 1.99 |
| 335.41 | 2.90 | 2.90 |
| 369.85 | 3.55 | 3.55 |
| 360.42 | 2.77 | 2.77 |
| 365.43 | 2.91 | 2.91 |
| 365.43 | 2.91 | 2.91 |
| 365.43 | 2.91 | 2.91 |
| 404.30 | 4.20 | 4.20 |
| 383.42 | 3.04 | 3.04 |
| 383.42 | 3.04 | 3.04 |