Basic Information
ID: ALA2352238
Type: Binding
Description: Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2352238
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 222.29 | 1.57 | 1.57 |
| 288.35 | 3.08 | 3.08 |
| 407.90 | 4.67 | 4.67 |
| 332.36 | 3.34 | 3.34 |
| 428.32 | 4.93 | 4.93 |
| 269.30 | 1.57 | 1.57 |
| 280.33 | 1.37 | 1.37 |
| 342.40 | 3.19 | 3.19 |
| 370.45 | 2.98 | 2.98 |
| 415.45 | 3.28 | 3.28 |
| 300.20 | 2.94 | 2.94 |
| 381.31 | 5.22 | 5.22 |
| 379.85 | 3.89 | 3.89 |
| 393.87 | 4.28 | 4.28 |
| 407.90 | 4.67 | 4.67 |
| 435.95 | 5.45 | 5.45 |
| 393.87 | 4.28 | 4.28 |
| 407.90 | 4.66 | 4.66 |
| 442.35 | 5.32 | 5.32 |
| 442.35 | 5.32 | 5.32 |
| 442.35 | 5.32 | 5.32 |
| 472.33 | 4.38 | 4.38 |
| 456.37 | 5.71 | 5.71 |
| 488.44 | 5.66 | 5.66 |
| 450.34 | 6.80 | 6.80 |
| 452.35 | 4.78 | 4.78 |
| 480.41 | 5.56 | 5.56 |
| 452.35 | 4.77 | 4.77 |
| 466.38 | 5.16 | 5.16 |
| 482.33 | 3.84 | 3.84 |
| 458.36 | 5.82 | 5.82 |
| 363.39 | 3.37 | 3.37 |
| 377.42 | 3.76 | 3.76 |
| 391.45 | 4.15 | 4.15 |
| 373.46 | 3.75 | 3.75 |
| 473.53 | 3.76 | 3.76 |
| 431.49 | 3.64 | 3.64 |
| 404.43 | 3.53 | 3.53 |
| 432.48 | 4.31 | 4.31 |
| 469.51 | 5.81 | 5.81 |
| 466.38 | 4.86 | 4.86 |
| 405.47 | 4.24 | 4.24 |