Basic Information
ID: ALA2352545
Type: Binding
Description: Inhibition of human recombinant caspase 7 assessed as decrease in AMC release using Ac-Asp-Glu-Val-Asp-AMC as substrate preincubated with enzyme for 10 mins prior to substrate addition measured after 10 mins by fluorescence microplate analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2352545
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 338.39 | 1.01 | 1.01 |
| 394.49 | 2.21 | 2.21 |
| 412.48 | 2.16 | 2.16 |
| 352.41 | 1.40 | 1.40 |
| 408.52 | 2.60 | 2.60 |
| 426.51 | 2.55 | 2.55 |
| 338.39 | 1.01 | 1.01 |
| 394.49 | 2.21 | 2.21 |
| 412.48 | 2.16 | 2.16 |
| 356.38 | 0.96 | 0.96 |
| 412.48 | 2.16 | 2.16 |
| 430.47 | 2.10 | 2.10 |
| 392.36 | 1.55 | 1.55 |
| 448.46 | 2.75 | 2.75 |
| 466.45 | 2.70 | 2.70 |