Basic Information
ID: ALA2353183
Type: Binding
Description: Inhibition of human BACE1 using MR121-labeled substrate incubated for 4 mins prior to substrate addition measured after 2 mins by spectrophotometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2353183
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.34 | 2.19 | 2.19 |
| 439.34 | 3.18 | 3.18 |
| 439.34 | 3.17 | 3.17 |
| 439.34 | 3.17 | 3.17 |
| 407.33 | 2.49 | 2.49 |
| 494.37 | 3.95 | 3.95 |
| 412.80 | 3.63 | 3.63 |
| 433.22 | 3.98 | 3.98 |
| 399.76 | 2.72 | 2.72 |
| 395.34 | 2.07 | 2.07 |
| 463.34 | 3.00 | 3.00 |
| 419.36 | 2.08 | 2.08 |
| 433.39 | 2.47 | 2.47 |
| 367.33 | 2.01 | 2.01 |
| 401.78 | 2.66 | 2.66 |
| 403.31 | 2.87 | 2.87 |
| 437.76 | 3.52 | 3.52 |
| 353.36 | 2.29 | 2.29 |
| 371.35 | 2.24 | 2.24 |
| 371.35 | 2.24 | 2.24 |
| 389.34 | 2.54 | 2.54 |
| 421.35 | 3.23 | 3.23 |
| 421.35 | 3.23 | 3.23 |
| 362.79 | 3.08 | 3.08 |
| 398.77 | 3.32 | 3.32 |
| 378.86 | 3.79 | 3.79 |
| 414.84 | 4.04 | 4.04 |
| 364.33 | 2.67 | 2.67 |
| 382.32 | 2.81 | 2.81 |
| 389.34 | 2.54 | 2.54 |
| 378.35 | 2.98 | 2.98 |
| 388.35 | 2.65 | 2.65 |
| 394.35 | 2.68 | 2.68 |
| 448.32 | 3.57 | 3.57 |
| 408.38 | 3.07 | 3.07 |
| 462.35 | 3.61 | 3.61 |
| 272.80 | 2.36 | 2.36 |