Basic Information
ID: ALA2353250
Type: Binding
Description: Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 mins prior to 1,10-phenanthroline-challenge measured after 16 hrs by luciferase reporter assay
Organism: Homo sapiens
Cell type: T47D
Activity Charts
Bioactivity
Activity Types for Assay ALA2353250
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 298.38 | 4.86 | 4.86 |
| 335.45 | 4.40 | 4.40 |
| 332.40 | 3.03 | 3.03 |
| 444.52 | 4.25 | 4.25 |
| 346.42 | 3.68 | 3.68 |
| 314.38 | 3.84 | 3.84 |
| 350.84 | 4.28 | 4.28 |
| 328.41 | 4.87 | 4.87 |
| 458.60 | 5.94 | 5.94 |
| 500.68 | 7.11 | 7.11 |
| 570.81 | 9.06 | 9.06 |
| 594.83 | 9.39 | 9.39 |
| 596.85 | 9.62 | 9.62 |