Basic Information
ID: ALA2353886
Type: Binding
Description: Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5 mins prior to substrate addition by fluorescence assay in presence of BSA
Organism: Cryptosporidium parvum
Activity Charts
Bioactivity
Activity Types for Assay ALA2353886
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.86 | 5.34 | 5.34 |
| 428.28 | 5.60 | 5.60 |
| 343.39 | 4.38 | 4.38 |
| 428.28 | 5.60 | 5.60 |
| 434.30 | 5.66 | 5.66 |
| 462.72 | 6.26 | 6.26 |
| 358.40 | 4.03 | 4.03 |
| 430.29 | 5.05 | 5.05 |
| 357.41 | 4.71 | 4.71 |
| 343.39 | 4.63 | 4.63 |
| 343.39 | 4.63 | 4.63 |
| 343.39 | 4.63 | 4.63 |
| 412.28 | 5.94 | 5.94 |
| 427.29 | 5.64 | 5.64 |
| 427.29 | 5.64 | 5.64 |
| 408.46 | 5.48 | 5.48 |
| 428.28 | 5.60 | 5.60 |
| 461.83 | 5.97 | 5.97 |
| 438.83 | 4.86 | 4.86 |
| 419.44 | 4.31 | 4.31 |
| 427.29 | 6.21 | 6.21 |
| 428.28 | 5.60 | 5.60 |
| 428.28 | 5.60 | 5.60 |
| 434.30 | 5.66 | 5.66 |
| 415.47 | 5.51 | 5.51 |
| 449.92 | 6.16 | 6.16 |
| 434.30 | 5.66 | 5.66 |
| 397.43 | 5.38 | 5.38 |
| 410.43 | 4.84 | 4.84 |
| 389.44 | 4.67 | 4.67 |
| 429.50 | 5.53 | 5.53 |
| 393.83 | 4.95 | 4.95 |
| 393.83 | 4.95 | 4.95 |
| 359.39 | 4.30 | 4.30 |
| 389.41 | 4.30 | 4.30 |
| 393.83 | 4.95 | 4.95 |
| 428.28 | 5.60 | 5.60 |
| 428.28 | 5.60 | 5.60 |
| 409.45 | 5.45 | 5.45 |
| 443.89 | 6.10 | 6.10 |
| 414.25 | 5.21 | 5.21 |
| 437.50 | 6.09 | 6.09 |
| 409.45 | 5.45 | 5.45 |
| 409.45 | 5.45 | 5.45 |