Basic Information
ID: ALA2354217
Type: Functional
Description: PubChem BioAssay. Counterscreen for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis: Fluorescence-based biochemical high throughput Glycerophosphate Dehydrogenase-Triosephosphate Isomerase (GDH-TPI) dose response assay to identify assay artifacts. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA2354217
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 228.25 | 2.98 | 2.98 |
| 367.47 | 3.12 | 3.12 |
| 222.24 | 3.46 | 3.46 |
| 270.34 | 4.89 | 4.89 |
| 252.27 | 3.31 | 3.31 |
| 467.66 | 4.35 | 4.35 |
| 302.38 | 4.43 | 4.43 |
| 401.49 | 2.55 | 2.55 |
| 371.86 | 2.66 | 2.66 |
| 261.30 | 2.77 | 2.77 |
| 260.25 | 0.69 | 0.69 |
| 369.51 | 1.64 | 1.64 |
| 410.47 | 3.14 | 3.14 |
| 432.59 | 3.90 | 3.90 |
| 393.87 | 2.55 | 2.55 |
| 397.38 | 1.87 | 1.87 |
| 337.36 | 3.91 | 3.91 |
| 250.31 | 2.89 | 2.89 |
| 337.31 | 1.59 | 1.59 |
| 238.29 | 3.69 | 3.69 |
| 348.22 | 4.73 | 4.73 |
| 310.36 | 2.91 | 2.91 |
| 407.00 | 2.60 | 2.60 |
| 276.32 | 1.72 | 1.72 |
| 351.21 | 4.03 | 4.03 |
| 398.42 | 3.61 | 3.61 |
| 287.32 | 2.10 | 2.10 |
| 439.47 | 2.20 | 2.20 |
| 513.65 | 3.19 | 3.19 |
| 265.29 | 2.39 | 2.39 |
| 217.22 | 2.25 | 2.25 |
| 351.82 | 1.45 | 1.45 |
| 379.49 | 4.86 | 4.86 |
| 320.35 | 2.85 | 2.85 |
| 410.45 | 0.63 | 0.63 |
| 262.25 | 1.00 | 1.00 |
| 216.27 | 2.39 | 2.39 |
| 280.33 | 3.68 | 3.68 |
| 365.39 | 3.41 | 3.41 |
| 214.29 | 3.30 | 3.30 |
| 256.26 | 2.86 | 2.86 |
| 200.67 | 0.54 | 0.54 |
| 350.25 | 3.19 | 3.19 |
| 376.36 | 4.59 | 4.59 |
| 302.38 | 4.94 | 4.94 |
| 487.55 | 4.22 | 4.22 |
| 399.90 | 3.92 | 3.92 |
| 359.38 | 2.12 | 2.12 |
| 228.27 | 0.55 | 0.55 |
| 418.50 | 3.18 | 3.18 |
| 471.48 | 3.56 | 3.56 |
| 330.84 | 4.17 | 4.17 |
| 469.58 | 6.25 | 6.25 |
| 537.97 | 7.24 | 7.24 |
| 373.43 | 2.79 | 2.79 |
| 224.26 | 3.39 | 3.39 |
| 304.82 | 3.44 | 3.44 |
| 322.37 | 2.23 | 2.23 |
| 230.65 | 2.98 | 2.98 |
| 278.30 | 2.37 | 2.37 |
| 358.43 | 1.83 | 1.83 |
| 389.89 | 5.33 | 5.33 |
| 317.37 | 1.72 | 1.72 |
| 318.83 | 4.13 | 4.13 |
| 397.43 | 3.34 | 3.34 |
| 259.70 | 2.34 | 2.34 |
| 444.51 | 2.10 | 2.10 |
| 280.32 | 3.72 | 3.72 |
| 448.50 | 2.60 | 2.60 |
| 249.32 | 3.47 | 3.47 |
| 306.33 | 2.69 | 2.69 |
| 260.30 | 4.35 | 4.35 |
| 197.24 | 1.82 | 1.82 |
| 429.48 | 3.86 | 3.86 |
| 232.24 | 1.18 | 1.18 |
| 285.30 | 2.64 | 2.64 |
| 213.24 | 2.61 | 2.61 |
| 404.51 | 4.94 | 4.94 |
| 254.29 | 2.40 | 2.40 |
| 345.40 | 3.36 | 3.36 |
| 335.40 | 4.62 | 4.62 |
| 282.30 | 1.70 | 1.70 |
| 439.57 | 3.66 | 3.66 |
| 450.50 | 3.37 | 3.37 |
| 367.49 | 4.01 | 4.01 |
| 310.31 | 2.13 | 2.13 |
| 407.52 | 2.56 | 2.56 |
| 450.50 | 3.04 | 3.04 |
| 357.48 | 2.35 | 2.35 |
| 432.48 | 5.11 | 5.11 |
| 497.62 | 3.77 | 3.77 |
| 273.32 | 2.36 | 2.36 |
| 420.56 | 3.64 | 3.64 |
| 450.45 | 3.66 | 3.66 |
| 362.45 | 5.93 | 5.93 |
| 363.39 | 1.83 | 1.83 |
| 309.42 | 4.37 | 4.37 |
| 367.40 | 2.64 | 2.64 |
| 350.45 | 3.60 | 3.60 |
| 232.24 | 1.26 | 1.26 |
| 363.46 | 4.26 | 4.26 |
| 279.30 | 4.02 | 4.02 |
| 238.29 | 2.62 | 2.62 |
| 297.42 | 4.04 | 4.04 |
| 237.72 | 2.94 | 2.94 |
| 315.38 | 2.06 | 2.06 |
| 233.22 | 1.16 | 1.16 |
| 298.35 | 2.62 | 2.62 |
| 445.47 | 3.90 | 3.90 |
| 424.49 | 1.94 | 1.94 |
| 497.08 | 5.36 | 5.36 |
| 377.42 | 1.73 | 1.73 |
| 211.27 | 2.58 | 2.58 |
| 321.36 | 4.20 | 4.20 |
| 225.25 | 2.67 | 2.67 |
| 433.51 | 6.23 | 6.23 |
| 279.36 | 1.68 | 1.68 |
| 376.28 | 3.83 | 3.83 |
| 395.20 | 4.05 | 4.05 |
| 423.47 | 2.12 | 2.12 |
| 444.51 | 5.78 | 5.78 |
| 261.33 | 3.14 | 3.14 |
| 429.97 | 4.46 | 4.46 |
| 328.32 | 3.62 | 3.62 |
| 290.32 | 2.40 | 2.40 |
| 253.31 | 2.97 | 2.97 |
| 393.49 | 4.08 | 4.08 |
| 261.28 | 1.53 | 1.53 |
| 421.45 | 3.07 | 3.07 |
| 262.29 | 1.31 | 1.31 |
| 448.56 | 4.21 | 4.21 |
| 419.53 | 3.61 | 3.61 |
| 376.44 | 4.47 | 4.47 |
| 411.45 | 4.55 | 4.55 |
| 397.43 | 4.15 | 4.15 |
| 297.32 | 1.77 | 1.77 |
| 471.51 | ||
| 417.47 | 2.83 | 2.83 |
| 388.46 | 2.02 | 2.02 |
| 357.41 | 0.22 | 0.22 |
| 252.73 | 3.64 | 3.64 |
| 252.32 | 2.68 | 2.68 |
| 341.41 | 1.99 | 1.99 |
| 267.29 | 2.64 | 2.64 |
| 236.27 | 3.10 | 3.10 |
| 287.32 | 2.10 | 2.10 |
| 327.38 | 4.13 | 4.13 |
| 295.34 | 3.79 | 3.79 |
| 410.47 | 2.55 | 2.55 |
| 245.31 | 2.78 | 2.78 |
| 284.32 | 2.46 | 2.46 |
| 407.48 | 4.41 | 4.41 |
| 393.51 | 3.89 | 3.89 |
| 467.55 | 3.39 | 3.39 |
| 206.24 | 2.39 | 2.39 |
| 406.87 | 2.57 | 2.57 |
| 322.32 | 3.79 | 3.79 |
| 283.38 | 1.94 | 1.94 |
| 221.26 | 2.90 | 2.90 |
| 201.23 | 1.60 | 1.60 |
| 433.51 | 4.16 | 4.16 |
| 367.41 | 1.55 | 1.55 |
| 374.40 | 3.81 | 3.81 |
| 342.35 | 5.76 | 5.76 |
| 369.38 | 1.03 | 1.03 |
| 259.30 | 2.40 | 2.40 |
| 226.24 | 1.05 | 1.05 |
| 329.43 | 4.87 | 4.87 |
| 384.26 | 4.80 | 4.80 |
| 300.75 | 2.67 | 2.67 |
| 328.38 | 4.19 | 4.19 |
| 230.27 | 1.12 | 1.12 |
| 247.30 | 4.30 | 4.30 |
| 294.31 | 2.77 | 2.77 |