ID: ALA2354222
Type: Functional
Description: PubChem BioAssay. Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): Luminescence-based cell-based high throughput dose response assay for nonselective inhibitors/assay artifacts using AP2 mutant SF-1 (NR5A1) Transactivation Assay. (Class of assay: confirmatory)
Bioactivity
Activity Types for Assay ALA2354222
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
414.41 | 2.41 | 2.41 |
301.33 | 3.03 | 3.03 |
264.32 | 2.47 | 2.47 |
399.44 | 2.87 | 2.87 |
254.24 | 2.87 | 2.87 |
427.45 | 2.68 | 2.68 |
507.49 | 2.69 | 2.69 |
429.47 | 3.48 | 3.48 |
280.36 | 1.96 | 1.96 |
282.30 | 3.48 | 3.48 |
373.47 | 3.41 | 3.41 |
327.18 | 4.09 | 4.09 |
410.51 | 1.52 | 1.52 |
300.27 | 2.59 | 2.59 |
360.32 | 2.60 | 2.60 |
414.41 | 2.41 | 2.41 |
371.43 | 2.95 | 2.95 |
401.48 | 3.28 | 3.28 |
254.36 | 3.94 | 3.94 |
909.07 | 3.99 | 3.99 |
380.35 | 3.63 | 3.63 |
285.27 | 3.36 | 3.36 |
923.05 | 3.52 | 3.52 |
468.54 | 3.50 | 3.50 |
297.31 | 3.05 | 3.05 |
257.29 | 2.96 | 2.96 |
219.67 | 0.35 | 0.35 |
248.31 | 1.86 | 1.86 |
340.35 | 2.76 | 2.76 |
279.30 | 2.79 | 2.79 |
295.30 | 3.00 | 3.00 |
341.44 | 3.47 | 3.47 |
348.41 | 3.08 | 3.08 |
325.33 | 1.76 | 1.76 |
458.97 | 4.21 | 4.21 |
284.71 | 2.93 | 2.93 |
218.21 | 1.94 | 1.94 |
375.45 | 2.60 | 2.60 |
322.46 | 3.31 | 3.31 |
333.39 | 4.73 | 4.73 |
272.33 | 3.76 | 3.76 |
343.86 | 3.15 | 3.15 |
296.33 | 2.70 | 2.70 |
283.36 | 3.56 | 3.56 |
337.47 | 3.95 | 3.95 |
332.43 | 2.86 | 2.86 |
422.53 | 2.58 | 2.58 |
440.57 | 4.27 | 4.27 |
410.54 | 4.04 | 4.04 |
312.37 | 3.20 | 3.20 |
553.14 | 5.49 | 5.49 |
415.45 | 5.10 | 5.10 |
280.37 | 3.84 | 3.84 |
273.30 | 4.73 | 4.73 |
353.40 | 2.80 | 2.80 |
431.51 | 1.91 | 1.91 |
284.33 | 3.68 | 3.68 |
426.52 | 4.46 | 4.46 |
346.18 | 3.99 | 3.99 |
259.35 | 3.32 | 3.32 |
287.75 | 3.29 | 3.29 |
364.52 | 3.62 | 3.62 |
327.17 | 3.12 | 3.12 |
307.39 | 4.29 | 4.29 |
396.45 | 2.39 | 2.39 |
292.34 | 3.80 | 3.80 |
374.44 | 3.29 | 3.29 |
404.87 | 4.70 | 4.70 |
266.35 | 3.45 | 3.45 |
434.50 | 2.81 | 2.81 |
315.37 | 3.64 | 3.64 |
377.44 | 3.38 | 3.38 |
291.33 | 2.64 | 2.64 |
415.49 | 3.21 | 3.21 |
390.44 | 3.00 | 3.00 |
282.34 | 2.90 | 2.90 |
403.49 | 2.91 | 2.91 |
275.74 | 2.81 | 2.81 |
367.45 | 3.56 | 3.56 |
352.44 | 2.98 | 2.98 |
363.42 | 2.95 | 2.95 |
272.30 | 1.59 | 1.59 |
451.59 | 5.26 | 5.26 |
282.30 | 3.48 | 3.48 |
512.52 | 5.04 | 5.04 |
331.20 | 3.14 | 3.14 |
357.21 | 4.01 | 4.01 |
280.80 | 4.57 | 4.57 |
346.18 | 3.12 | 3.12 |
293.43 | 3.17 | 3.17 |
348.41 | 6.22 | 6.22 |
288.35 | 3.50 | 3.50 |
267.29 | 2.37 | 2.37 |
421.50 | 3.92 | 3.92 |
474.03 | 4.15 | 4.15 |
339.42 | 3.35 | 3.35 |
344.46 | 3.76 | 3.76 |
375.47 | 2.58 | 2.58 |
256.30 | 2.89 | 2.89 |
437.93 | 3.57 | 3.57 |
307.34 | 0.71 | 0.71 |
273.31 | 3.29 | 3.29 |
296.28 | 2.52 | 2.52 |
302.38 | 4.24 | 4.24 |
255.28 | 1.97 | 1.97 |
256.28 | 3.46 | 3.46 |
301.33 | 3.06 | 3.06 |
300.39 | 3.43 | 3.43 |
402.48 | 3.80 | 3.80 |
289.33 | 2.66 | 2.66 |
438.53 | 4.17 | 4.17 |
292.36 | 2.41 | 2.41 |
244.21 | -3.17 | -3.17 |
481.62 | 4.03 | 4.03 |
473.55 | 3.92 | 3.92 |
312.33 | 1.84 | 1.84 |
496.36 | 4.94 | 4.94 |
298.37 | 3.08 | 3.08 |
318.40 | 2.10 | 2.10 |
303.29 | 2.61 | 2.61 |
361.42 | 1.66 | 1.66 |
368.46 | 4.35 | 4.35 |
306.75 | 4.34 | 4.34 |
422.53 | 2.53 | 2.53 |
325.42 | 5.47 | 5.47 |
320.37 | 2.22 | 2.22 |
265.76 | 3.76 | 3.76 |
376.57 | 4.75 | 4.75 |
438.60 | 3.55 | 3.55 |
387.44 | 3.31 | 3.31 |
528.07 | 3.35 | 3.35 |
390.37 | 2.94 | 2.94 |
277.75 | 3.52 | 3.52 |
346.45 | 3.36 | 3.36 |
298.37 | 3.74 | 3.74 |
259.38 | 4.42 | 4.42 |
428.89 | 2.09 | 2.09 |
263.23 | 2.08 | 2.08 |
308.43 | 2.85 | 2.85 |
309.43 | 2.64 | 2.64 |
251.35 | 4.78 | 4.78 |
320.18 | 5.23 | 5.23 |
436.54 | 3.15 | 3.15 |
306.70 | 2.79 | 2.79 |
365.48 | 3.37 | 3.37 |
243.33 | 3.87 | 3.87 |
388.14 | 4.35 | 4.35 |
294.31 | 3.22 | 3.22 |
298.29 | 3.95 | 3.95 |
265.32 | 3.15 | 3.15 |
283.35 | 3.80 | 3.80 |
422.53 | 2.96 | 2.96 |
257.32 | 2.15 | 2.15 |
425.46 | 3.09 | 3.09 |
249.22 | 3.37 | 3.37 |
308.82 | 4.57 | 4.57 |
231.32 | 2.25 | 2.25 |
307.78 | 3.56 | 3.56 |
321.40 | 3.96 | 3.96 |
345.45 | 3.84 | 3.84 |
362.45 | 1.59 | 1.59 |
484.02 | 5.23 | 5.23 |
224.26 | 2.89 | 2.89 |
360.41 | 3.94 | 3.94 |
391.45 | 3.89 | 3.89 |
337.36 | 4.00 | 4.00 |
290.34 | 3.49 | 3.49 |
433.55 | 4.94 | 4.94 |
309.36 | 3.72 | 3.72 |
269.33 | 2.86 | 2.86 |
274.30 | 3.15 | 3.15 |
292.40 | 1.96 | 1.96 |
445.54 | 4.19 | 4.19 |
524.60 | 3.54 | 3.54 |
326.35 | 2.18 | 2.18 |
531.63 | 3.53 | 3.53 |
328.37 | 3.01 | 3.01 |
299.36 | 3.86 | 3.86 |
385.42 | 2.57 | 2.57 |
785.11 | 5.19 | 5.19 |
270.34 | 4.89 | 4.89 |
327.37 | 2.80 | 2.80 |
367.45 | 3.51 | 3.51 |
447.60 | 3.85 | 3.85 |
291.37 | 3.05 | 3.05 |
449.53 | 4.91 | 4.91 |
364.49 | 5.47 | 5.47 |
677.33 | 2.49 | 2.49 |
429.47 | 2.97 | 2.97 |
414.57 | 3.99 | 3.99 |
461.51 | 4.17 | 4.17 |
923.05 | 3.52 | 3.52 |
306.37 | 3.33 | 3.33 |
473.61 | 4.55 | 4.55 |
259.26 | 2.33 | 2.33 |
403.44 | 4.26 | 4.26 |
428.46 | 4.67 | 4.67 |
268.74 | 4.55 | 4.55 |
387.44 | 3.33 | 3.33 |
417.47 | 4.57 | 4.57 |
264.32 | 3.91 | 3.91 |
293.37 | 3.73 | 3.73 |
352.23 | 2.96 | 2.96 |
397.70 | 6.01 | 6.01 |
324.41 | 5.19 | 5.19 |
433.46 | 4.27 | 4.27 |
265.27 | 3.73 | 3.73 |
334.79 | 2.67 | 2.67 |
264.32 | 3.91 | 3.91 |
258.35 | 2.01 | 2.01 |
276.73 | 2.97 | 2.97 |
231.28 | 1.91 | 1.91 |
377.40 | 2.92 | 2.92 |
283.33 | 3.10 | 3.10 |
260.32 | 2.61 | 2.61 |
269.26 | 1.57 | 1.57 |
377.29 | 5.66 | 5.66 |
391.31 | 5.97 | 5.97 |
351.41 | 2.10 | 2.10 |
324.36 | 3.47 | 3.47 |
332.36 | 4.96 | 4.96 |
372.42 | 3.57 | 3.57 |
312.39 | 3.39 | 3.39 |
433.46 | 4.27 | 4.27 |
434.99 | 4.33 | 4.33 |
403.73 | 6.07 | 6.07 |
385.42 | 3.16 | 3.16 |
328.44 | 3.88 | 3.88 |
377.29 | 5.66 | 5.66 |
330.34 | 2.98 | 2.98 |
366.40 | 3.04 | 3.04 |
507.63 | 2.92 | 2.92 |
338.39 | 3.02 | 3.02 |
281.27 | 3.21 | 3.21 |
996.29 | 4.94 | 4.94 |
283.29 | 2.99 | 2.99 |
414.53 | 3.20 | 3.20 |
359.23 | 3.05 | 3.05 |
251.29 | 3.58 | 3.58 |
353.30 | 3.24 | 3.24 |
232.28 | 2.43 | 2.43 |
285.32 | 2.66 | 2.66 |
259.33 | 2.48 | 2.48 |
291.31 | 3.41 | 3.41 |
266.31 | 2.31 | 2.31 |
336.21 | 2.14 | 2.14 |
298.34 | 3.07 | 3.07 |
265.11 | 3.05 | 3.05 |
419.41 | 3.96 | 3.96 |