Basic Information
ID: ALA2354265
Type: Functional
Description: PubChem BioAssay. Counterscreen for antagonists of the galanin Receptor 3 (GalR3): Fluorescence-based cell-based high throughput dose response assay to identify non specific activators of the parental HEK-CNG cells. (Class of assay: confirmatory)
Cell type: HEK-CNG
Activity Charts
Bioactivity
Activity Types for Assay ALA2354265
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.44 | 3.78 | 3.78 |
| 392.47 | 1.90 | 1.90 |
| 307.31 | -0.96 | -0.96 |
| 181.24 | 1.04 | 1.04 |
| 424.68 | 3.20 | 3.20 |
| 309.28 | -2.28 | -2.28 |
| 235.29 | 3.24 | 3.24 |
| 256.74 | 4.05 | 4.05 |
| 325.35 | -1.74 | -1.74 |
| 400.02 | 3.69 | 3.69 |
| 251.33 | 3.90 | 3.90 |
| 364.94 | 5.24 | 5.24 |
| 339.32 | 3.53 | 3.53 |
| 367.38 | 4.31 | 4.31 |
| 370.67 | 3.03 | 3.03 |
| 233.28 | 1.13 | 1.13 |
| 301.27 | 3.72 | 3.72 |
| 603.76 | 4.11 | 4.11 |
| 397.39 | 2.10 | 2.10 |
| 195.69 | 0.64 | 0.64 |
| 323.82 | 2.35 | 2.35 |
| 529.11 | 3.88 | 3.88 |
| 296.37 | 3.36 | 3.36 |
| 310.37 | 4.85 | 4.85 |
| 420.44 | 3.75 | 3.75 |
| 414.89 | 3.87 | 3.87 |
| 478.55 | 2.57 | 2.57 |
| 377.44 | 2.83 | 2.83 |
| 461.39 | 4.50 | 4.50 |
| 502.42 | 5.45 | 5.45 |
| 298.41 | 4.64 | 4.64 |
| 244.30 | 0.94 | 0.94 |
| 186.17 | 0.03 | 0.03 |
| 304.31 | 3.82 | 3.82 |
| 514.91 | 4.41 | 4.41 |
| 393.44 | 1.81 | 1.81 |
| 387.87 | 4.43 | 4.43 |
| 353.42 | 3.26 | 3.26 |
| 298.17 | 2.97 | 2.97 |
| 307.40 | 1.45 | 1.45 |
| 299.29 | 1.75 | 1.75 |
| 402.36 | 3.81 | 3.81 |
| 418.50 | 1.97 | 1.97 |
| 237.26 | 2.36 | 2.36 |
| 398.50 | 3.34 | 3.34 |
| 381.43 | 3.30 | 3.30 |
| 437.41 | 5.20 | 5.20 |
| 360.87 | 4.81 | 4.81 |
| 400.55 | 2.57 | 2.57 |
| 422.47 | 2.30 | 2.30 |
| 351.44 | 2.37 | 2.37 |
| 427.96 | 4.91 | 4.91 |
| 315.59 | 4.22 | 4.22 |
| 271.35 | 2.51 | 2.51 |
| 307.42 | 3.76 | 3.76 |
| 358.38 | 2.61 | 2.61 |
| 422.93 | 3.49 | 3.49 |
| 285.12 | 0.58 | 0.58 |
| 320.27 | 2.71 | 2.71 |
| 417.47 | 3.88 | 3.88 |
| 343.45 | 3.01 | 3.01 |
| 387.18 | 0.41 | 0.41 |
| 561.73 | 3.55 | 3.55 |
| 243.33 | 2.94 | 2.94 |
| 304.24 | 2.71 | 2.71 |
| 416.42 | 4.51 | 4.51 |
| 276.30 | 1.52 | 1.52 |
| 300.77 | 3.45 | 3.45 |
| 382.49 | 1.86 | 1.86 |
| 360.48 | 3.68 | 3.68 |
| 433.51 | 3.06 | 3.06 |
| 296.37 | 3.36 | 3.36 |
| 475.55 | 2.88 | 2.88 |
| 354.45 | 2.77 | 2.77 |
| 423.47 | 3.75 | 3.75 |
| 311.39 | 2.66 | 2.66 |
| 319.41 | 1.61 | 1.61 |
| 363.47 | 3.51 | 3.51 |
| 496.61 | 3.57 | 3.57 |
| 487.64 | 5.57 | 5.57 |
| 340.36 | 2.04 | 2.04 |
| 469.57 | 6.27 | 6.27 |
| 508.32 | 5.99 | 5.99 |
| 210.24 | 2.63 | 2.63 |
| 335.20 | 3.48 | 3.48 |
| 320.38 | 3.64 | 3.64 |
| 343.43 | 3.20 | 3.20 |
| 502.42 | 5.45 | 5.45 |
| 380.48 | 3.31 | 3.31 |
| 315.40 | 3.36 | 3.36 |
| 332.36 | 3.33 | 3.33 |
| 432.59 | 5.37 | 5.37 |
| 331.33 | 2.74 | 2.74 |
| 226.11 | 0.26 | 0.26 |
| 292.39 | 4.37 | 4.37 |
| 494.62 | 4.26 | 4.26 |
| 330.74 | 1.80 | 1.80 |
| 372.45 | 3.29 | 3.29 |
| 464.54 | 2.18 | 2.18 |
| 271.75 | 3.24 | 3.24 |
| 348.26 | 2.68 | 2.68 |
| 405.31 | 5.00 | 5.00 |
| 431.56 | 5.42 | 5.42 |
| 278.27 | 3.66 | 3.66 |
| 371.53 | 3.85 | 3.85 |
| 347.42 | 4.82 | 4.82 |
| 262.19 | -0.33 | -0.33 |
| 467.79 | 5.18 | 5.18 |
| 276.34 | 3.72 | 3.72 |
| 377.49 | 3.71 | 3.71 |
| 259.28 | 3.38 | 3.38 |
| 492.45 | 5.49 | 5.49 |
| 202.24 | 2.55 | 2.55 |
| 465.34 | 4.26 | 4.26 |
| 314.39 | 3.52 | 3.52 |
| 214.57 | 1.18 | 1.18 |
| 397.37 | 0.66 | 0.66 |
| 418.49 | 3.76 | 3.76 |
| 281.31 | 2.57 | 2.57 |
| 348.62 | 4.44 | 4.44 |
| 395.43 | 5.09 | 5.09 |
| 317.00 | 3.51 | 3.51 |
| 379.47 | 3.88 | 3.88 |
| 310.31 | 2.15 | 2.15 |
| 324.41 | 3.37 | 3.37 |
| 301.82 | 2.75 | 2.75 |
| 326.81 | 2.61 | 2.61 |
| 357.36 | 2.69 | 2.69 |
| 524.67 | 2.10 | 2.10 |
| 389.82 | 4.34 | 4.34 |
| 490.98 | 4.84 | 4.84 |
| 345.04 | 4.00 | 4.00 |
| 297.36 | 2.40 | 2.40 |
| 435.65 | 4.79 | 4.79 |
| 368.43 | 3.35 | 3.35 |
| 422.46 | 1.99 | 1.99 |
| 359.43 | 3.68 | 3.68 |
| 308.35 | 3.31 | 3.31 |
| 315.37 | 2.38 | 2.38 |
| 461.50 | 3.27 | 3.27 |
| 297.39 | 3.07 | 3.07 |
| 363.89 | 3.41 | 3.41 |
| 536.12 | 4.45 | 4.45 |
| 427.49 | 3.08 | 3.08 |
| 433.35 | 4.53 | 4.53 |
| 427.29 | 2.01 | 2.01 |
| 347.39 | 2.65 | 2.65 |
| 333.23 | 2.38 | 2.38 |
| 432.48 | 3.94 | 3.94 |
| 382.75 | 4.57 | 4.57 |
| 356.38 | 3.88 | 3.88 |
| 417.37 | 2.72 | 2.72 |
| 561.73 | 3.55 | 3.55 |
| 395.42 | 2.97 | 2.97 |
| 343.35 | 4.89 | 4.89 |
| 424.93 | 4.23 | 4.23 |
| 449.36 | 5.93 | 5.93 |
| 248.24 | 1.04 | 1.04 |
| 474.52 | 4.33 | 4.33 |
| 328.21 | 3.94 | 3.94 |
| 274.32 | 3.76 | 3.76 |
| 249.32 | 3.80 | 3.80 |
| 434.95 | 5.00 | 5.00 |
| 362.42 | 2.29 | 2.29 |
| 380.43 | 3.45 | 3.45 |
| 327.42 | 4.53 | 4.53 |
| 399.45 | 3.90 | 3.90 |
| 344.47 | 3.33 | 3.33 |
| 362.48 | 2.61 | 2.61 |
| 292.30 | 0.86 | 0.86 |
| 202.17 | 0.71 | 0.71 |
| 501.54 | 5.15 | 5.15 |
| 470.04 | 5.32 | 5.32 |
| 435.50 | 4.87 | 4.87 |
| 327.30 | -2.28 | -2.28 |
| 435.38 | 5.66 | 5.66 |
| 467.55 | 5.31 | 5.31 |
| 433.39 | 5.52 | 5.52 |
| 385.42 | 1.22 | 1.22 |
| 481.57 | 3.58 | 3.58 |
| 367.45 | 4.08 | 4.08 |
| 365.89 | 3.67 | 3.67 |
| 375.47 | 4.03 | 4.03 |
| 250.71 | -0.09 | -0.09 |
| 278.31 | 3.25 | 3.25 |
| 236.32 | 3.70 | 3.70 |
| 390.23 | 3.95 | 3.95 |
| 380.49 | 2.93 | 2.93 |
| 357.80 | 2.73 | 2.73 |
| 334.38 | 4.20 | 4.20 |
| 396.45 | 1.27 | 1.27 |
| 383.34 | 4.33 | 4.33 |
| 483.62 | 3.71 | 3.71 |
| 231.63 | 1.63 | 1.63 |
| 461.49 | 4.59 | 4.59 |
| 484.60 | 3.67 | 3.67 |
| 262.74 | 2.68 | 2.68 |
| 391.56 | 3.86 | 3.86 |
| 300.31 | 3.74 | 3.74 |
| 396.44 | 3.78 | 3.78 |
| 505.56 | 3.41 | 3.41 |
| 301.19 | 4.16 | 4.16 |
| 692.80 | 0.84 | 0.84 |
| 399.56 | 3.81 | 3.81 |
| 245.66 | 0.26 | 0.26 |
| 1059.40 | ||
| 370.43 | 3.70 | 3.70 |
| 456.45 | 5.10 | 5.10 |
| 388.42 | 4.44 | 4.44 |
| 583.58 | 1.80 | 1.80 |
| 257.36 | 3.19 | 3.19 |
| 338.66 | 3.81 | 3.81 |
| 373.77 | 3.52 | 3.52 |
| 376.49 | 4.63 | 4.63 |
| 484.60 | 4.24 | 4.24 |
| 395.17 | 2.23 | 2.23 |
| 431.49 | 5.36 | 5.36 |
| 460.61 | 4.54 | 4.54 |
| 453.50 | 0.07 | 0.07 |
| 570.69 | 5.53 | 5.53 |
| 401.69 | 5.91 | 5.91 |
| 353.43 | 4.41 | 4.41 |
| 475.62 | 3.04 | 3.04 |
| 207.30 | 2.06 | 2.06 |
| 412.47 | 3.37 | 3.37 |
| 413.35 | 4.70 | 4.70 |
| 435.24 | 6.27 | 6.27 |
| 524.39 | 1.80 | 1.80 |
| 392.38 | 6.36 | 6.36 |
| 396.90 | 4.18 | 4.18 |
| 404.50 | 1.90 | 1.90 |
| 329.39 | 3.84 | 3.84 |
| 404.47 | 3.96 | 3.96 |
| 471.47 | 4.14 | 4.14 |
| 522.43 | 6.89 | 6.89 |