Basic Information
ID: ALA2354274
Type: Functional
Description: PubChem BioAssay. Fluorescence-based biochemical high throughput dose response assay to identify molecules that bind r(CAG) RNA repeats. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA2354274
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 924.09 | 0.71 | 0.71 |
| 370.41 | 5.26 | 5.26 |
| 502.77 | 7.28 | 7.28 |
| 318.24 | 1.69 | 1.69 |
| 477.46 | -0.62 | -0.62 |
| 340.38 | 4.89 | 4.89 |
| 392.41 | 4.85 | 4.85 |
| 476.53 | 3.54 | 3.54 |
| 375.38 | 3.54 | 3.54 |
| 230.34 | 1.65 | 1.65 |
| 398.53 | 5.12 | 5.12 |
| 418.45 | 2.91 | 2.91 |
| 436.54 | 2.80 | 2.80 |
| 375.81 | 5.19 | 5.19 |
| 492.60 | 3.87 | 3.87 |
| 399.49 | 3.59 | 3.59 |
| 363.33 | 3.04 | 3.04 |
| 407.93 | 4.87 | 4.87 |
| 339.99 | 3.39 | 3.39 |
| 449.47 | 2.56 | 2.56 |
| 494.37 | 4.13 | 4.13 |
| 433.52 | 2.20 | 2.20 |
| 459.62 | 5.16 | 5.16 |
| 438.51 | 4.79 | 4.79 |
| 465.55 | 4.42 | 4.42 |
| 489.39 | 4.32 | 4.32 |
| 426.48 | 3.55 | 3.55 |
| 574.46 | 5.82 | 5.82 |
| 409.45 | 4.89 | 4.89 |
| 427.46 | 4.19 | 4.19 |
| 440.98 | 4.96 | 4.96 |
| 340.40 | 5.43 | 5.43 |
| 434.84 | 5.17 | 5.17 |
| 442.57 | 4.13 | 4.13 |
| 379.50 | 3.75 | 3.75 |
| 462.96 | 6.61 | 6.61 |
| 402.50 | 4.12 | 4.12 |
| 408.51 | 4.50 | 4.50 |
| 400.44 | 1.70 | 1.70 |
| 521.53 | 4.29 | 4.29 |
| 439.31 | 4.99 | 4.99 |
| 447.64 | 3.94 | 3.94 |
| 389.47 | 3.27 | 3.27 |
| 532.58 | 3.66 | 3.66 |
| 411.89 | 4.95 | 4.95 |
| 424.83 | 5.81 | 5.81 |
| 483.43 | 6.16 | 6.16 |
| 399.49 | 3.59 | 3.59 |
| 420.42 | 3.66 | 3.66 |
| 456.38 | 4.31 | 4.31 |
| 459.40 | 6.40 | 6.40 |
| 418.41 | 3.28 | 3.28 |
| 514.63 | 6.03 | 6.03 |
| 386.41 | 1.31 | 1.31 |
| 347.46 | 3.70 | 3.70 |
| 464.48 | 3.13 | 3.13 |
| 344.33 | 5.52 | 5.52 |
| 350.85 | 4.90 | 4.90 |
| 342.36 | 4.24 | 4.24 |
| 358.44 | 2.94 | 2.94 |
| 512.03 | 5.94 | 5.94 |
| 533.01 | 6.21 | 6.21 |
| 319.32 | 3.69 | 3.69 |
| 329.81 | 4.06 | 4.06 |
| 355.78 | 4.21 | 4.21 |
| 437.49 | 4.04 | 4.04 |
| 452.95 | 3.82 | 3.82 |
| 337.81 | 5.24 | 5.24 |
| 404.42 | 5.28 | 5.28 |
| 310.39 | 5.36 | 5.36 |
| 527.00 | 3.30 | 3.30 |
| 419.28 | 4.22 | 4.22 |
| 485.61 | 4.77 | 4.77 |
| 398.49 | 1.94 | 1.94 |
| 405.41 | 2.25 | 2.25 |
| 464.19 | 4.26 | 4.26 |
| 388.27 | 5.19 | 5.19 |
| 428.54 | 4.02 | 4.02 |
| 371.48 | 5.55 | 5.55 |
| 304.37 | 2.26 | 2.26 |
| 498.00 | 3.89 | 3.89 |
| 435.50 | 3.26 | 3.26 |
| 298.35 | 3.30 | 3.30 |
| 375.48 | 3.41 | 3.41 |
| 520.62 | 6.57 | 6.57 |
| 386.82 | 3.70 | 3.70 |
| 422.92 | 3.81 | 3.81 |
| 380.92 | 4.48 | 4.48 |
| 483.33 | 3.05 | 3.05 |
| 408.42 | 4.65 | 4.65 |
| 325.11 | 3.19 | 3.19 |
| 422.92 | 4.44 | 4.44 |
| 361.49 | 3.94 | 3.94 |
| 366.44 | 4.45 | 4.45 |
| 406.89 | 4.34 | 4.34 |
| 466.52 | 2.92 | 2.92 |
| 484.63 | 4.20 | 4.20 |
| 472.50 | 3.04 | 3.04 |
| 446.71 | 2.72 | 2.72 |
| 373.42 | 1.79 | 1.79 |
| 430.87 | 4.43 | 4.43 |
| 296.35 | 3.92 | 3.92 |
| 405.47 | 3.54 | 3.54 |
| 518.57 | 3.31 | 3.31 |
| 362.35 | 1.16 | 1.16 |
| 365.22 | 3.02 | 3.02 |
| 394.46 | 4.00 | 4.00 |
| 315.12 | 0.57 | 0.57 |
| 384.46 | 4.35 | 4.35 |
| 373.87 | 4.70 | 4.70 |
| 341.36 | 4.50 | 4.50 |
| 324.73 | 3.24 | 3.24 |
| 509.90 | 6.50 | 6.50 |
| 363.45 | 3.48 | 3.48 |
| 448.49 | 5.41 | 5.41 |
| 417.36 | 3.63 | 3.63 |
| 385.45 | 3.65 | 3.65 |
| 483.46 | 3.83 | 3.83 |
| 325.15 | 4.34 | 4.34 |
| 370.43 | 3.57 | 3.57 |
| 323.37 | 4.37 | 4.37 |
| 612.78 | 5.84 | 5.84 |
| 350.49 | 3.71 | 3.71 |
| 447.95 | 2.83 | 2.83 |
| 414.49 | 3.92 | 3.92 |
| 384.50 | 4.72 | 4.72 |
| 389.82 | 4.34 | 4.34 |
| 594.05 | 4.36 | 4.36 |
| 375.79 | 4.04 | 4.04 |
| 355.80 | 5.01 | 5.01 |
| 452.24 | 3.94 | 3.94 |
| 440.52 | 4.55 | 4.55 |
| 442.33 | 5.55 | 5.55 |
| 426.84 | 4.92 | 4.92 |
| 403.46 | 3.69 | 3.69 |
| 429.93 | 4.66 | 4.66 |
| 465.34 | 4.75 | 4.75 |
| 443.95 | 5.82 | 5.82 |
| 360.44 | 4.85 | 4.85 |
| 510.48 | 4.88 | 4.88 |
| 372.28 | 2.86 | 2.86 |
| 428.45 | 2.55 | 2.55 |
| 292.42 | 5.20 | 5.20 |
| 485.54 | 4.19 | 4.19 |
| 405.52 | 4.39 | 4.39 |
| 286.40 | 2.38 | 2.38 |
| 405.48 | 4.84 | 4.84 |
| 443.46 | 4.54 | 4.54 |
| 309.33 | 4.31 | 4.31 |
| 401.51 | 4.37 | 4.37 |
| 503.61 | 3.36 | 3.36 |
| 452.60 | 5.48 | 5.48 |
| 349.42 | 4.46 | 4.46 |
| 476.52 | 3.00 | 3.00 |
| 406.47 | 3.88 | 3.88 |
| 432.47 | 4.40 | 4.40 |
| 399.93 | 5.14 | 5.14 |
| 489.55 | 4.78 | 4.78 |
| 418.45 | 2.91 | 2.91 |
| 449.53 | 3.65 | 3.65 |
| 403.23 | 4.07 | 4.07 |
| 449.86 | 4.20 | 4.20 |
| 383.81 | 2.89 | 2.89 |
| 448.48 | 4.04 | 4.04 |
| 509.52 | 2.70 | 2.70 |
| 330.34 | 4.38 | 4.38 |
| 237.61 | 2.16 | 2.16 |
| 466.97 | 3.88 | 3.88 |
| 480.54 | 5.13 | 5.13 |
| 470.33 | 4.42 | 4.42 |
| 406.56 | 4.69 | 4.69 |
| 578.47 | 5.99 | 5.99 |
| 341.16 | 4.35 | 4.35 |
| 415.51 | 4.78 | 4.78 |
| 429.93 | 4.47 | 4.47 |
| 447.45 | 0.58 | 0.58 |
| 508.50 | 5.80 | 5.80 |
| 457.91 | 3.90 | 3.90 |
| 576.65 | 5.46 | 5.46 |
| 464.54 | 4.72 | 4.72 |
| 277.37 | 3.73 | 3.73 |
| 429.51 | 4.41 | 4.41 |
| 435.42 | 4.80 | 4.80 |
| 372.06 | 4.88 | 4.88 |
| 384.32 | 2.86 | 2.86 |
| 388.45 | 3.33 | 3.33 |
| 511.57 | 5.09 | 5.09 |
| 403.48 | 4.25 | 4.25 |
| 495.67 | 6.24 | 6.24 |
| 430.92 | 3.87 | 3.87 |
| 439.58 | 5.01 | 5.01 |
| 406.19 | 4.52 | 4.52 |
| 518.42 | 5.89 | 5.89 |
| 458.54 | 5.96 | 5.96 |
| 504.45 | 5.46 | 5.46 |
| 714.68 | 2.70 | 2.70 |
| 794.98 | 2.41 | 2.41 |
| 467.97 | 5.54 | 5.54 |
| 514.03 | 5.37 | 5.37 |
| 303.57 | 4.65 | 4.65 |
| 570.65 | 4.46 | 4.46 |
| 470.64 | 4.15 | 4.15 |
| 497.02 | 4.41 | 4.41 |
| 576.65 | 5.46 | 5.46 |
| 480.51 | 3.75 | 3.75 |
| 362.37 | 1.05 | 1.05 |
| 385.47 | 3.55 | 3.55 |
| 485.96 | 5.68 | 5.68 |
| 538.70 | 4.67 | 4.67 |
| 374.40 | 3.82 | 3.82 |
| 482.00 | 5.84 | 5.84 |
| 316.31 | 3.26 | 3.26 |
| 420.44 | 5.62 | 5.62 |
| 358.39 | 4.46 | 4.46 |
| 492.91 | 4.02 | 4.02 |
| 414.49 | 4.37 | 4.37 |
| 478.53 | 4.94 | 4.94 |
| 185.19 | 1.99 | 1.99 |
| 484.14 | 4.93 | 4.93 |
| 391.47 | 2.82 | 2.82 |
| 380.86 | 4.16 | 4.16 |
| 370.87 | 4.26 | 4.26 |
| 474.54 | 5.36 | 5.36 |
| 492.51 | 4.70 | 4.70 |
| 503.05 | 4.30 | 4.30 |
| 584.73 | 4.99 | 4.99 |
| 463.27 | 6.82 | 6.82 |
| 497.02 | 4.19 | 4.19 |
| 517.63 | 4.20 | 4.20 |
| 569.73 | 5.19 | 5.19 |
| 668.75 | 6.61 | 6.61 |
| 488.47 | 3.12 | 3.12 |
| 490.58 | 3.33 | 3.33 |
| 437.34 | 3.43 | 3.43 |
| 430.56 | 3.85 | 3.85 |
| 459.89 | 4.78 | 4.78 |
| 406.92 | 3.51 | 3.51 |
| 480.98 | 4.95 | 4.95 |
| 459.53 | 2.43 | 2.43 |
| 445.18 | 3.68 | 3.68 |
| 329.75 | 1.29 | 1.29 |
| 468.54 | 5.07 | 5.07 |
| 329.74 | 3.45 | 3.45 |
| 402.50 | 4.21 | 4.21 |
| 465.58 | 3.61 | 3.61 |
| 414.51 | 3.32 | 3.32 |
| 255.36 | 2.73 | 2.73 |