Basic Information
ID: ALA2354289
Type: Functional
Description: PubChem BioAssay. Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA2354289
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 231.09 | 1.81 | 1.81 |
| 210.28 | 2.38 | 2.38 |
| 137.18 | 0.89 | 0.89 |
| 254.33 | 2.03 | 2.03 |
| 401.87 | 2.73 | 2.73 |
| 335.45 | 2.27 | 2.27 |
| 249.27 | 0.99 | 0.99 |
| 219.24 | 0.99 | 0.99 |
| 253.69 | 1.64 | 1.64 |
| 213.24 | 2.73 | 2.73 |
| 231.23 | 2.86 | 2.86 |
| 173.22 | 2.00 | 2.00 |
| 430.56 | 2.45 | 2.45 |
| 239.28 | 2.01 | 2.01 |
| 332.79 | 2.48 | 2.48 |
| 196.68 | 1.23 | 1.23 |
| 316.79 | 2.78 | 2.78 |
| 361.85 | 3.71 | 3.71 |
| 346.82 | 2.79 | 2.79 |
| 356.86 | 3.98 | 3.98 |
| 307.18 | 3.61 | 3.61 |
| 370.67 | 3.03 | 3.03 |
| 246.74 | 2.38 | 2.38 |
| 477.55 | 3.11 | 3.11 |
| 337.76 | 2.45 | 2.45 |
| 300.79 | 3.57 | 3.57 |
| 262.32 | 3.01 | 3.01 |
| 349.81 | 2.65 | 2.65 |
| 162.20 | 0.50 | 0.50 |
| 236.75 | 2.11 | 2.11 |
| 363.35 | 2.69 | 2.69 |
| 232.12 | 1.28 | 1.28 |
| 171.63 | 0.83 | 0.83 |
| 237.16 | 2.47 | 2.47 |
| 169.65 | 1.50 | 1.50 |
| 328.23 | 2.39 | 2.39 |
| 301.82 | 2.69 | 2.69 |
| 349.45 | 1.72 | 1.72 |
| 405.92 | 3.77 | 3.77 |
| 407.50 | 2.64 | 2.64 |
| 255.32 | 1.51 | 1.51 |
| 302.38 | 4.43 | 4.43 |
| 365.26 | 3.74 | 3.74 |
| 301.82 | 3.82 | 3.82 |
| 233.27 | 1.37 | 1.37 |
| 519.46 | 4.71 | 4.71 |
| 263.75 | 3.32 | 3.32 |
| 215.30 | 2.46 | 2.46 |
| 371.83 | 3.48 | 3.48 |
| 274.28 | 1.15 | 1.15 |
| 370.43 | 1.27 | 1.27 |
| 235.29 | 3.30 | 3.30 |
| 335.41 | 3.12 | 3.12 |
| 373.88 | 3.13 | 3.13 |
| 275.35 | 2.24 | 2.24 |
| 365.87 | 3.56 | 3.56 |
| 401.51 | 4.27 | 4.27 |
| 429.52 | 3.17 | 3.17 |
| 376.46 | 3.28 | 3.28 |
| 441.96 | 3.65 | 3.65 |
| 276.38 | 4.03 | 4.03 |
| 373.88 | 3.52 | 3.52 |
| 267.32 | -0.35 | -0.35 |
| 309.37 | 2.17 | 2.17 |
| 321.38 | 2.66 | 2.66 |
| 449.98 | 4.72 | 4.72 |
| 215.26 | 1.84 | 1.84 |
| 369.49 | 3.43 | 3.43 |
| 285.30 | 1.85 | 1.85 |
| 347.37 | 2.50 | 2.50 |
| 334.47 | 4.50 | 4.50 |
| 221.33 | 2.63 | 2.63 |
| 286.40 | 2.79 | 2.79 |
| 305.38 | 0.96 | 0.96 |
| 285.36 | 1.89 | 1.89 |
| 356.31 | 1.77 | 1.77 |
| 474.57 | 3.36 | 3.36 |
| 303.41 | 2.38 | 2.38 |
| 288.30 | 2.94 | 2.94 |
| 417.42 | 3.84 | 3.84 |
| 206.31 | 2.44 | 2.44 |
| 333.39 | 2.40 | 2.40 |
| 231.23 | 2.86 | 2.86 |
| 361.47 | 0.83 | 0.83 |
| 332.32 | 1.78 | 1.78 |
| 188.19 | 1.32 | 1.32 |
| 381.43 | 2.81 | 2.81 |
| 303.32 | 2.68 | 2.68 |
| 397.50 | 3.79 | 3.79 |
| 310.38 | 3.59 | 3.59 |
| 387.91 | 3.74 | 3.74 |
| 418.54 | 3.67 | 3.67 |
| 373.43 | 0.76 | 0.76 |
| 333.89 | 4.05 | 4.05 |
| 377.49 | 4.24 | 4.24 |
| 305.35 | 2.23 | 2.23 |
| 387.52 | 3.93 | 3.93 |
| 478.85 | 5.52 | 5.52 |
| 317.43 | 2.37 | 2.37 |
| 437.34 | 4.79 | 4.79 |
| 303.36 | 3.40 | 3.40 |
| 163.22 | 1.36 | 1.36 |
| 315.34 | 2.27 | 2.27 |
| 405.55 | 3.04 | 3.04 |
| 371.22 | 3.72 | 3.72 |
| 265.76 | 3.37 | 3.37 |
| 329.51 | 4.52 | 4.52 |
| 384.43 | 2.40 | 2.40 |
| 325.26 | 4.52 | 4.52 |
| 297.35 | 2.66 | 2.66 |
| 321.87 | 3.81 | 3.81 |
| 257.30 | 1.92 | 1.92 |
| 280.33 | 3.03 | 3.03 |
| 364.34 | 2.31 | 2.31 |
| 271.32 | 2.31 | 2.31 |
| 321.76 | 1.65 | 1.65 |
| 224.74 | 2.53 | 2.53 |
| 291.39 | 2.74 | 2.74 |
| 336.82 | 3.33 | 3.33 |
| 413.95 | 2.82 | 2.82 |
| 195.29 | 0.98 | 0.98 |
| 424.52 | 3.46 | 3.46 |
| 271.28 | 2.76 | 2.76 |
| 564.55 | 2.60 | 2.60 |
| 327.45 | 3.26 | 3.26 |
| 223.27 | 1.63 | 1.63 |
| 328.44 | 3.46 | 3.46 |
| 393.47 | 2.20 | 2.20 |
| 243.14 | 2.47 | 2.47 |
| 432.93 | 3.58 | 3.58 |
| 350.31 | 1.92 | 1.92 |
| 429.52 | 3.42 | 3.42 |
| 201.66 | 1.00 | 1.00 |
| 432.57 | 4.06 | 4.06 |
| 362.41 | 0.14 | 0.14 |
| 203.67 | 0.90 | 0.90 |
| 220.26 | 2.18 | 2.18 |
| 327.45 | 3.26 | 3.26 |
| 271.28 | 0.70 | 0.70 |
| 269.30 | 3.29 | 3.29 |
| 525.08 | 3.61 | 3.61 |
| 443.61 | 2.34 | 2.34 |
| 369.44 | 3.58 | 3.58 |
| 302.38 | 0.56 | 0.56 |
| 301.39 | 2.79 | 2.79 |
| 498.94 | 4.32 | 4.32 |
| 358.36 | 2.39 | 2.39 |
| 318.37 | 2.74 | 2.74 |
| 300.36 | 2.37 | 2.37 |
| 172.66 | 0.84 | 0.84 |
| 347.42 | 2.72 | 2.72 |
| 378.87 | 3.89 | 3.89 |
| 249.38 | 2.07 | 2.07 |
| 402.20 | 2.76 | 2.76 |
| 403.55 | 5.21 | 5.21 |
| 449.46 | 1.96 | 1.96 |
| 330.34 | 2.66 | 2.66 |
| 350.37 | 2.71 | 2.71 |
| 424.38 | 3.70 | 3.70 |
| 313.40 | 2.48 | 2.48 |
| 485.03 | 4.03 | 4.03 |
| 185.70 | 2.01 | 2.01 |
| 270.29 | 2.57 | 2.57 |
| 367.49 | 3.87 | 3.87 |
| 412.51 | 3.23 | 3.23 |
| 325.43 | 4.48 | 4.48 |
| 330.86 | 3.38 | 3.38 |
| 402.47 | 1.85 | 1.85 |
| 421.45 | 3.05 | 3.05 |
| 327.38 | 2.10 | 2.10 |
| 253.69 | 1.64 | 1.64 |
| 314.34 | 2.87 | 2.87 |
| 259.31 | 0.74 | 0.74 |
| 273.33 | 2.01 | 2.01 |
| 413.95 | 3.67 | 3.67 |
| 180.28 | 2.12 | 2.12 |
| 311.45 | 3.56 | 3.56 |
| 261.30 | 2.16 | 2.16 |
| 301.37 | 1.86 | 1.86 |
| 496.66 | 5.03 | 5.03 |
| 482.59 | 5.07 | 5.07 |
| 208.69 | 1.81 | 1.81 |
| 376.43 | 1.31 | 1.31 |
| 290.73 | 3.09 | 3.09 |
| 272.74 | 2.96 | 2.96 |
| 342.46 | 3.82 | 3.82 |
| 275.78 | 3.77 | 3.77 |
| 421.50 | 3.26 | 3.26 |
| 309.79 | 2.89 | 2.89 |
| 346.70 | 3.75 | 3.75 |
| 354.41 | 3.84 | 3.84 |
| 279.34 | 2.35 | 2.35 |
| 325.48 | 3.81 | 3.81 |
| 328.37 | 2.01 | 2.01 |
| 355.48 | 3.93 | 3.93 |
| 431.92 | 2.18 | 2.18 |
| 483.06 | 3.57 | 3.57 |
| 306.41 | 3.89 | 3.89 |
| 332.79 | 2.48 | 2.48 |
| 409.81 | 5.25 | 5.25 |
| 314.18 | 2.66 | 2.66 |
| 293.41 | 2.84 | 2.84 |
| 385.27 | 4.21 | 4.21 |
| 268.32 | 1.22 | 1.22 |
| 327.38 | 2.33 | 2.33 |
| 290.43 | 2.60 | 2.60 |
| 321.35 | 4.66 | 4.66 |
| 393.41 | 3.48 | 3.48 |
| 396.56 | 3.92 | 3.92 |
| 344.33 | 2.00 | 2.00 |
| 287.32 | 0.85 | 0.85 |
| 343.38 | 3.88 | 3.88 |
| 306.41 | 3.89 | 3.89 |
| 240.76 | 2.31 | 2.31 |
| 385.53 | 4.39 | 4.39 |
| 319.79 | 2.52 | 2.52 |
| 313.37 | 0.47 | 0.47 |
| 254.29 | 3.53 | 3.53 |
| 407.52 | 2.97 | 2.97 |
| 439.49 | 3.40 | 3.40 |
| 369.46 | 2.89 | 2.89 |
| 263.41 | 2.46 | 2.46 |
| 467.25 | 4.85 | 4.85 |
| 359.47 | 4.58 | 4.58 |
| 376.96 | 3.76 | 3.76 |
| 231.25 | 1.54 | 1.54 |
| 271.32 | 3.03 | 3.03 |
| 275.74 | 3.67 | 3.67 |
| 232.30 | 2.50 | 2.50 |
| 269.34 | 2.96 | 2.96 |
| 215.21 | 2.49 | 2.49 |
| 229.67 | 3.23 | 3.23 |
| 456.32 | 4.40 | 4.40 |
| 380.45 | 3.78 | 3.78 |
| 296.46 | 3.85 | 3.85 |
| 269.34 | 2.60 | 2.60 |
| 383.50 | 1.16 | 1.16 |
| 348.45 | 4.12 | 4.12 |
| 283.37 | 3.20 | 3.20 |
| 268.76 | 2.50 | 2.50 |
| 381.43 | 2.34 | 2.34 |
| 285.34 | 1.87 | 1.87 |
| 466.60 | 4.61 | 4.61 |
| 357.40 | 2.18 | 2.18 |
| 397.49 | 2.31 | 2.31 |
| 347.84 | 3.11 | 3.11 |
| 366.42 | 2.53 | 2.53 |
| 259.30 | 1.30 | 1.30 |
| 320.44 | 4.20 | 4.20 |
| 417.49 | 0.51 | 0.51 |
| 283.40 | 2.80 | 2.80 |
| 301.37 | 1.32 | 1.32 |
| 280.33 | 4.00 | 4.00 |
| 345.70 | 2.95 | 2.95 |
| 417.54 | 4.30 | 4.30 |
| 406.49 | 2.21 | 2.21 |
| 388.86 | 2.95 | 2.95 |
| 401.46 | 3.51 | 3.51 |
| 233.27 | 1.38 | 1.38 |
| 475.52 | 0.28 | 0.28 |
| 360.24 | 3.72 | 3.72 |
| 203.20 | 2.32 | 2.32 |
| 275.35 | 2.24 | 2.24 |
| 308.41 | 1.98 | 1.98 |
| 308.47 | 2.46 | 2.46 |
| 353.41 | 2.32 | 2.32 |
| 226.28 | 2.67 | 2.67 |
| 280.37 | 3.84 | 3.84 |
| 346.35 | 2.17 | 2.17 |
| 303.39 | 1.94 | 1.94 |
| 375.48 | 2.25 | 2.25 |
| 327.42 | 3.04 | 3.04 |
| 409.92 | 2.71 | 2.71 |
| 406.46 | 1.32 | 1.32 |
| 461.54 | 0.83 | 0.83 |
| 386.51 | 3.38 | 3.38 |
| 293.34 | 0.30 | 0.30 |
| 293.37 | 2.85 | 2.85 |
| 219.22 | 2.37 | 2.37 |
| 477.56 | 4.76 | 4.76 |
| 365.81 | 3.55 | 3.55 |
| 307.39 | 3.54 | 3.54 |
| 228.30 | 2.59 | 2.59 |
| 354.34 | 2.46 | 2.46 |
| 309.20 | 3.67 | 3.67 |
| 289.37 | 2.80 | 2.80 |
| 353.41 | 3.36 | 3.36 |
| 366.49 | 2.83 | 2.83 |
| 276.77 | 3.07 | 3.07 |
| 259.78 | 2.96 | 2.96 |
| 371.36 | 4.29 | 4.29 |
| 359.45 | 2.04 | 2.04 |
| 367.43 | 3.04 | 3.04 |
| 392.48 | 2.92 | 2.92 |
| 213.28 | 3.23 | 3.23 |
| 403.28 | 3.61 | 3.61 |
| 230.23 | 1.33 | 1.33 |
| 397.18 | 0.92 | 0.92 |
| 394.54 | 3.45 | 3.45 |
| 373.48 | 2.28 | 2.28 |
| 332.45 | 4.76 | 4.76 |
| 342.53 | 4.02 | 4.02 |
| 247.29 | 2.59 | 2.59 |
| 321.80 | 2.75 | 2.75 |
| 250.33 | 2.31 | 2.31 |
| 293.34 | 2.38 | 2.38 |
| 287.36 | 2.09 | 2.09 |
| 285.34 | 2.68 | 2.68 |
| 223.70 | 2.64 | 2.64 |
| 369.39 | 3.19 | 3.19 |
| 356.45 | 3.51 | 3.51 |
| 289.38 | 2.52 | 2.52 |
| 244.25 | 1.64 | 1.64 |
| 330.30 | 1.18 | 1.18 |
| 504.63 | 4.41 | 4.41 |
| 534.61 | 3.75 | 3.75 |
| 466.48 | 5.28 | 5.28 |
| 548.64 | 4.14 | 4.14 |
| 522.69 | 5.10 | 5.10 |
| 431.90 | 3.19 | 3.19 |
| 562.66 | 4.38 | 4.38 |
| 556.62 | 4.84 | 4.84 |
| 231.29 | 2.88 | 2.88 |
| 526.72 | 5.57 | 5.57 |
| 486.01 | 3.45 | 3.45 |
| 561.60 | -0.03 | -0.03 |
| 649.07 | 3.43 | 3.43 |
| 625.07 | 3.49 | 3.49 |
| 470.01 | 3.75 | 3.75 |
| 460.02 | 3.46 | 3.46 |
| 527.38 | 5.76 | 5.76 |
| 366.46 | 1.47 | 1.47 |
| 619.04 | 3.43 | 3.43 |
| 325.42 | 2.62 | 2.62 |
| 375.35 | 3.77 | 3.77 |
| 448.01 | 3.32 | 3.32 |
| 508.66 | 4.71 | 4.71 |
| 502.08 | 4.43 | 4.43 |
| 490.00 | 4.16 | 4.16 |
| 457.96 | 3.48 | 3.48 |
| 524.88 | 4.75 | 4.75 |
| 528.02 | 3.27 | 3.27 |
| 496.05 | 4.43 | 4.43 |
| 496.03 | 4.22 | 4.22 |
| 462.03 | 3.71 | 3.71 |
| 414.42 | -0.76 | -0.76 |
| 254.34 | 1.48 | 1.48 |
| 300.43 | 3.18 | 3.18 |
| 294.44 | 3.49 | 3.49 |
| 687.93 | 4.73 | 4.73 |
| 206.25 | 1.80 | 1.80 |
| 266.35 | 2.13 | 2.13 |
| 496.05 | 4.37 | 4.37 |
| 520.03 | 4.17 | 4.17 |
| 562.04 | 3.99 | 3.99 |
| 670.76 | 4.57 | 4.57 |
| 562.71 | 4.67 | 4.67 |
| 584.80 | 5.83 | 5.83 |
| 524.88 | 4.75 | 4.75 |
| 464.48 | 4.93 | 4.93 |
| 382.49 | 2.85 | 2.85 |
| 479.96 | 3.75 | 3.75 |
| 464.01 | 3.68 | 3.68 |
| 482.93 | 5.65 | 5.65 |
| 504.03 | 4.47 | 4.47 |
| 587.00 | 2.74 | 2.74 |
| 596.81 | 5.97 | 5.97 |
| 455.99 | 3.44 | 3.44 |
| 583.01 | 2.52 | 2.52 |
| 409.49 | 1.17 | 1.17 |
| 419.95 | 2.54 | 2.54 |
| 526.08 | 4.38 | 4.38 |
| 505.06 | 2.98 | 2.98 |
| 611.06 | 3.30 | 3.30 |
| 687.93 | 4.73 | 4.73 |
| 359.35 | 4.07 | 4.07 |
| 373.40 | 2.42 | 2.42 |
| 276.34 | 3.47 | 3.47 |
| 296.37 | 3.01 | 3.01 |
| 259.74 | 3.71 | 3.71 |
| 280.67 | 1.69 | 1.69 |
| 332.34 | 2.33 | 2.33 |
| 313.36 | 1.77 | 1.77 |
| 325.34 | 2.37 | 2.37 |
| 287.36 | 3.21 | 3.21 |
| 346.43 | 2.71 | 2.71 |
| 341.80 | 2.89 | 2.89 |
| 329.36 | 1.48 | 1.48 |
| 313.74 | 3.75 | 3.75 |
| 284.34 | 2.25 | 2.25 |
| 422.41 | 1.96 | 1.96 |
| 254.70 | 2.34 | 2.34 |
| 262.70 | 2.59 | 2.59 |
| 311.38 | 3.44 | 3.44 |
| 349.81 | 2.96 | 2.96 |
| 289.25 | -0.32 | -0.32 |
| 353.35 | 3.30 | 3.30 |
| 277.33 | 3.69 | 3.69 |
| 261.35 | 2.78 | 2.78 |
| 324.86 | 4.54 | 4.54 |
| 268.73 | 2.65 | 2.65 |
| 325.34 | 2.37 | 2.37 |
| 311.38 | 3.44 | 3.44 |
| 307.33 | 1.62 | 1.62 |
| 449.59 | 5.91 | 5.91 |
| 273.25 | -0.02 | -0.02 |
| 388.45 | 0.82 | 0.82 |
| 243.31 | 2.87 | 2.87 |
| 248.67 | 2.28 | 2.28 |
| 225.29 | 3.05 | 3.05 |
| 257.33 | 3.26 | 3.26 |
| 269.34 | 3.24 | 3.24 |
| 269.30 | 2.65 | 2.65 |
| 321.36 | 1.93 | 1.93 |