Basic Information
ID: ALA2354291
Type: Functional
Description: PubChem BioAssay. qHTS for inhibitors of Phosphogylcerate Kinase: Hit Validation Screen. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA2354291
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 562.67 | 7.50 | 7.50 |
| 464.38 | -0.54 | -0.54 |
| 208.22 | 2.73 | 2.73 |
| 223.23 | 2.31 | 2.31 |
| 240.21 | 1.87 | 1.87 |
| 297.27 | 2.30 | 2.30 |
| 318.24 | 1.69 | 1.69 |
| 360.32 | 1.76 | 1.76 |
| 220.18 | 1.02 | 1.02 |
| 282.30 | 2.23 | 2.23 |
| 197.19 | 0.05 | 0.05 |
| 224.22 | 2.76 | 2.76 |
| 239.23 | 1.75 | 1.75 |
| 299.31 | -1.69 | -1.69 |
| 288.31 | 3.36 | 3.36 |
| 258.28 | 3.36 | 3.36 |
| 458.47 | 3.96 | 3.96 |
| 300.27 | 2.59 | 2.59 |
| 258.23 | 2.32 | 2.32 |
| 386.31 | 2.32 | 2.32 |
| 228.21 | 0.97 | 0.97 |
| 294.15 | 2.99 | 2.99 |
| 400.36 | 2.93 | 2.93 |
| 316.29 | 3.18 | 3.18 |
| 444.45 | 3.02 | 3.02 |
| 264.33 | 3.75 | 3.75 |
| 302.24 | 1.99 | 1.99 |
| 345.38 | 3.54 | 3.54 |
| 328.35 | 2.72 | 2.72 |
| 230.22 | 2.03 | 2.03 |
| 430.53 | 4.62 | 4.62 |
| 337.42 | 3.15 | 3.15 |
| 309.37 | 2.51 | 2.51 |
| 475.53 | 4.47 | 4.47 |
| 302.36 | 3.85 | 3.85 |
| 288.33 | 3.46 | 3.46 |
| 272.31 | 3.66 | 3.66 |
| 453.46 | -0.54 | -0.54 |
| 349.96 | 3.04 | 3.04 |
| 348.31 | 2.69 | 2.69 |
| 224.22 | 2.19 | 2.19 |
| 253.26 | 2.81 | 2.81 |
| 506.48 | 6.09 | 6.09 |
| 220.28 | 3.73 | 3.73 |
| 330.29 | 1.53 | 1.53 |
| 362.90 | 5.04 | 5.04 |
| 207.19 | -1.32 | -1.32 |
| 193.17 | -1.63 | -1.63 |
| 309.33 | 1.03 | 1.03 |
| 266.25 | 2.73 | 2.73 |
| 320.25 | 1.99 | 1.99 |
| 445.45 | 0.48 | 0.48 |
| 437.19 | 3.21 | 3.21 |
| 315.35 | 3.54 | 3.54 |
| 422.49 | 2.28 | 2.28 |
| 333.39 | 3.54 | 3.54 |
| 298.30 | 2.41 | 2.41 |
| 487.51 | 5.41 | 5.41 |
| 251.33 | 3.06 | 3.06 |
| 306.36 | 3.44 | 3.44 |
| 407.29 | 3.16 | 3.16 |
| 255.07 | 2.89 | 2.89 |
| 385.45 | 3.36 | 3.36 |
| 265.18 | 0.28 | 0.28 |
| 262.27 | 3.11 | 3.11 |
| 242.23 | 2.71 | 2.71 |
| 256.31 | 3.15 | 3.15 |
| 415.54 | 3.77 | 3.77 |
| 364.40 | 3.52 | 3.52 |
| 472.50 | 3.33 | 3.33 |
| 344.37 | 1.64 | 1.64 |
| 571.58 | 3.15 | 3.15 |
| 284.27 | 2.88 | 2.88 |
| 372.43 | 3.09 | 3.09 |
| 294.29 | 1.56 | 1.56 |
| 415.45 | 2.37 | 2.37 |
| 277.71 | 3.26 | 3.26 |
| 260.25 | 1.47 | 1.47 |
| 235.25 | -0.67 | -0.67 |
| 380.35 | 3.70 | 3.70 |
| 494.04 | 3.14 | 3.14 |
| 298.32 | 2.11 | 2.11 |
| 343.34 | 4.02 | 4.02 |
| 432.48 | 2.46 | 2.46 |
| 490.54 | 5.25 | 5.25 |
| 305.37 | 3.02 | 3.02 |
| 209.27 | 1.28 | 1.28 |
| 303.16 | 3.65 | 3.65 |
| 410.47 | 2.12 | 2.12 |
| 488.01 | 6.33 | 6.33 |
| 271.28 | 1.57 | 1.57 |
| 236.28 | 3.99 | 3.99 |
| 262.29 | 2.12 | 2.12 |
| 246.27 | 1.06 | 1.06 |
| 407.81 | 3.93 | 3.93 |
| 300.31 | 3.43 | 3.43 |
| 444.45 | 3.02 | 3.02 |
| 195.22 | 1.52 | 1.52 |
| 152.11 | -0.22 | -0.22 |
| 376.37 | 3.88 | 3.88 |
| 522.47 | 2.28 | 2.28 |
| 552.34 | 3.92 | 3.92 |
| 395.25 | 2.50 | 2.50 |
| 862.75 | -1.10 | -1.10 |
| 427.33 | 4.45 | 4.45 |
| 457.46 | 3.49 | 3.49 |
| 209.20 | 0.11 | 0.11 |
| 384.44 | 3.02 | 3.02 |
| 265.18 | 0.28 | 0.28 |
| 410.47 | 2.12 | 2.12 |
| 477.90 | 4.11 | 4.11 |
| 183.12 | 1.29 | 1.29 |
| 292.32 | 1.58 | 1.58 |
| 862.75 | -1.10 | -1.10 |
| 246.34 | 3.26 | 3.26 |
| 435.95 | 4.11 | 4.11 |
| 449.54 | 3.83 | 3.83 |
| 260.32 | 2.74 | 2.74 |
| 238.25 | 3.08 | 3.08 |
| 436.99 | 6.51 | 6.51 |
| 485.50 | 3.80 | 3.80 |
| 396.45 | 1.73 | 1.73 |
| 487.51 | 5.41 | 5.41 |
| 275.26 | 1.75 | 1.75 |
| 453.40 | 4.41 | 4.41 |
| 495.34 | 4.44 | 4.44 |
| 322.32 | 3.34 | 3.34 |
| 476.55 | 5.02 | 5.02 |
| 255.25 | 2.95 | 2.95 |
| 349.84 | 1.59 | 1.59 |
| 457.27 | 5.04 | 5.04 |
| 346.41 | 1.83 | 1.83 |
| 396.41 | -1.07 | -1.07 |
| 462.48 | 4.63 | 4.63 |
| 458.45 | 3.57 | 3.57 |
| 470.94 | 1.09 | 1.09 |
| 304.37 | 2.21 | 2.21 |
| 279.35 | 4.05 | 4.05 |
| 505.35 | 3.90 | 3.90 |
| 308.44 | 0.69 | 0.69 |
| 557.26 | 5.32 | 5.32 |
| 254.35 | 4.27 | 4.27 |
| 413.46 | 2.12 | 2.12 |
| 267.24 | 2.53 | 2.53 |
| 417.45 | 3.75 | 3.75 |
| 415.45 | 3.92 | 3.92 |
| 241.25 | 1.77 | 1.77 |
| 278.29 | 1.89 | 1.89 |
| 272.37 | 3.35 | 3.35 |
| 232.29 | 3.58 | 3.58 |
| 315.37 | 5.11 | 5.11 |
| 292.34 | 3.61 | 3.61 |
| 271.28 | 1.16 | 1.16 |
| 499.55 | 5.28 | 5.28 |
| 334.40 | 2.70 | 2.70 |
| 390.49 | 3.02 | 3.02 |
| 412.31 | 3.65 | 3.65 |
| 367.34 | 1.86 | 1.86 |
| 277.32 | 2.09 | 2.09 |
| 323.33 | 2.69 | 2.69 |
| 410.74 | 4.54 | 4.54 |
| 224.21 | 1.23 | 1.23 |
| 448.88 | 4.04 | 4.04 |
| 493.50 | 3.54 | 3.54 |
| 357.42 | 2.78 | 2.78 |
| 289.36 | 2.02 | 2.02 |
| 255.28 | 1.87 | 1.87 |
| 433.25 | 3.46 | 3.46 |
| 208.17 | 0.25 | 0.25 |
| 473.32 | 4.24 | 4.24 |
| 232.31 | 2.87 | 2.87 |
| 414.48 | 3.11 | 3.11 |
| 404.49 | 4.67 | 4.67 |
| 402.44 | 3.22 | 3.22 |
| 490.92 | 3.80 | 3.80 |
| 356.37 | -0.72 | -0.72 |
| 536.50 | 2.59 | 2.59 |
| 349.30 | 4.50 | 4.50 |
| 425.47 | 2.83 | 2.83 |
| 261.24 | 0.44 | 0.44 |
| 313.34 | 1.10 | 1.10 |
| 258.28 | 2.42 | 2.42 |
| 498.56 | 1.55 | 1.55 |
| 494.60 | 4.07 | 4.07 |
| 485.50 | 3.80 | 3.80 |
| 392.48 | 2.93 | 2.93 |
| 166.18 | 0.96 | 0.96 |
| 288.69 | 2.33 | 2.33 |
| 278.33 | 2.56 | 2.56 |
| 594.52 | -1.39 | -1.39 |
| 330.34 | 3.67 | 3.67 |
| 304.37 | 2.26 | 2.26 |
| 322.30 | 0.67 | 0.67 |
| 366.37 | 3.42 | 3.42 |
| 407.81 | 3.93 | 3.93 |
| 213.24 | 3.51 | 3.51 |
| 444.45 | 3.02 | 3.02 |
| 245.27 | 1.15 | 1.15 |
| 296.28 | 2.25 | 2.25 |
| 342.90 | 2.31 | 2.31 |
| 310.69 | 2.49 | 2.49 |
| 316.31 | 0.62 | 0.62 |
| 386.79 | 2.65 | 2.65 |
| 500.51 | 3.99 | 3.99 |
| 378.43 | 3.91 | 3.91 |
| 223.23 | 1.27 | 1.27 |
| 529.60 | 2.83 | 2.83 |
| 646.59 | 3.96 | 3.96 |
| 506.49 | 4.36 | 4.36 |
| 406.80 | 4.20 | 4.20 |
| 408.40 | 1.79 | 1.79 |
| 299.33 | 3.04 | 3.04 |
| 443.24 | 5.05 | 5.05 |
| 339.35 | 2.92 | 2.92 |
| 285.30 | 1.96 | 1.96 |
| 336.30 | 3.11 | 3.11 |
| 254.29 | 2.47 | 2.47 |
| 316.31 | 2.25 | 2.25 |
| 378.91 | 4.09 | 4.09 |
| 271.28 | 1.57 | 1.57 |
| 400.49 | 4.07 | 4.07 |
| 321.35 | 2.16 | 2.16 |
| 267.29 | 2.82 | 2.82 |
| 301.30 | 1.27 | 1.27 |
| 382.89 | 2.95 | 2.95 |
| 258.23 | 2.42 | 2.42 |
| 360.31 | 3.95 | 3.95 |
| 232.31 | 3.01 | 3.01 |
| 239.27 | 2.88 | 2.88 |
| 254.29 | 2.30 | 2.30 |
| 453.45 | 5.79 | 5.79 |
| 270.25 | -0.56 | -0.56 |
| 234.19 | 0.13 | 0.13 |
| 410.47 | 1.95 | 1.95 |
| 289.18 | 3.31 | 3.31 |
| 246.27 | 4.04 | 4.04 |
| 289.72 | 2.52 | 2.52 |
| 307.29 | 1.85 | 1.85 |
| 536.08 | 4.60 | 4.60 |
| 346.47 | 3.60 | 3.60 |
| 290.34 | 1.26 | 1.26 |
| 216.24 | 2.54 | 2.54 |
| 288.76 | 4.00 | 4.00 |
| 302.28 | 1.32 | 1.32 |
| 514.52 | 3.95 | 3.95 |
| 269.30 | 2.18 | 2.18 |
| 404.37 | -3.26 | -3.26 |
| 342.38 | 2.51 | 2.51 |
| 253.26 | 2.81 | 2.81 |
| 256.30 | 3.04 | 3.04 |
| 276.30 | 2.57 | 2.57 |
| 526.53 | 4.11 | 4.11 |
| 314.39 | 2.71 | 2.71 |
| 430.53 | 4.62 | 4.62 |
| 441.47 | 4.95 | 4.95 |
| 361.31 | 3.04 | 3.04 |
| 237.26 | 3.11 | 3.11 |
| 234.11 | 2.89 | 2.89 |
| 353.33 | 1.90 | 1.90 |
| 378.39 | 3.92 | 3.92 |
| 480.47 | 1.57 | 1.57 |
| 212.25 | 3.14 | 3.14 |
| 426.29 | 3.04 | 3.04 |
| 382.37 | 2.24 | 2.24 |
| 285.34 | 2.97 | 2.97 |
| 316.34 | 2.50 | 2.50 |
| 316.32 | 4.54 | 4.54 |
| 418.45 | 2.91 | 2.91 |
| 309.37 | 3.57 | 3.57 |
| 299.24 | 2.78 | 2.78 |
| 288.25 | 2.22 | 2.22 |
| 212.63 | 2.98 | 2.98 |
| 478.36 | -0.45 | -0.45 |
| 308.41 | 3.34 | 3.34 |
| 353.38 | 1.96 | 1.96 |
| 312.34 | 3.31 | 3.31 |
| 536.12 | 5.73 | 5.73 |
| 374.70 | 3.54 | 3.54 |
| 313.38 | 3.55 | 3.55 |
| 486.53 | 4.26 | 4.26 |
| 557.46 | 7.03 | 7.03 |
| 426.52 | 2.73 | 2.73 |
| 536.63 | 4.37 | 4.37 |
| 229.26 | 2.86 | 2.86 |
| 287.34 | 2.16 | 2.16 |
| 420.47 | 5.35 | 5.35 |
| 228.23 | 3.71 | 3.71 |
| 476.58 | 4.35 | 4.35 |
| 294.29 | 1.56 | 1.56 |
| 328.30 | 2.12 | 2.12 |
| 443.44 | 3.29 | 3.29 |
| 516.58 | 1.82 | 1.82 |
| 284.34 | 3.56 | 3.56 |
| 471.54 | 3.79 | 3.79 |
| 244.25 | 2.07 | 2.07 |
| 275.70 | 2.42 | 2.42 |
| 231.25 | 1.93 | 1.93 |
| 287.27 | 2.30 | 2.30 |
| 245.28 | 2.23 | 2.23 |
| 262.38 | 3.30 | 3.30 |
| 396.31 | 3.24 | 3.24 |
| 285.25 | 2.02 | 2.02 |
| 438.55 | 5.61 | 5.61 |
| 296.39 | -1.11 | -1.11 |
| 487.47 | 3.47 | 3.47 |
| 490.54 | 5.25 | 5.25 |
| 432.72 | 3.91 | 3.91 |
| 288.10 | 0.87 | 0.87 |
| 314.18 | 2.66 | 2.66 |
| 315.81 | 3.02 | 3.02 |
| 358.44 | 3.72 | 3.72 |
| 240.33 | 3.96 | 3.96 |
| 314.33 | 2.31 | 2.31 |
| 258.31 | 2.35 | 2.35 |
| 291.31 | 2.92 | 2.92 |
| 297.14 | 3.41 | 3.41 |
| 283.33 | 3.51 | 3.51 |
| 404.43 | 2.52 | 2.52 |
| 262.29 | 1.09 | 1.09 |
| 393.36 | 1.98 | 1.98 |
| 292.38 | 1.75 | 1.75 |
| 449.98 | 4.28 | 4.28 |
| 329.26 | 2.36 | 2.36 |
| 362.45 | 2.72 | 2.72 |
| 326.31 | 1.95 | 1.95 |
| 404.43 | 2.52 | 2.52 |
| 434.95 | 5.00 | 5.00 |
| 256.26 | 2.37 | 2.37 |
| 405.50 | 3.01 | 3.01 |
| 455.94 | 5.63 | 5.63 |
| 407.30 | 3.54 | 3.54 |
| 454.89 | 2.15 | 2.15 |
| 281.66 | 0.78 | 0.78 |
| 491.43 | 3.30 | 3.30 |
| 405.82 | 3.94 | 3.94 |
| 373.37 | 3.27 | 3.27 |
| 354.32 | 0.95 | 0.95 |
| 275.70 | 2.42 | 2.42 |
| 438.71 | 2.53 | 2.53 |
| 365.30 | 3.59 | 3.59 |
| 263.25 | 2.12 | 2.12 |
| 294.31 | 3.32 | 3.32 |
| 383.43 | 2.90 | 2.90 |
| 235.33 | 1.06 | 1.06 |
| 473.38 | 4.95 | 4.95 |
| 459.51 | 2.41 | 2.41 |
| 257.29 | 2.43 | 2.43 |
| 296.46 | 3.70 | 3.70 |
| 307.35 | 2.01 | 2.01 |
| 361.42 | 3.05 | 3.05 |
| 196.20 | 0.98 | 0.98 |
| 312.87 | 2.71 | 2.71 |
| 323.40 | 2.90 | 2.90 |
| 257.32 | 2.15 | 2.15 |
| 385.47 | 3.73 | 3.73 |
| 368.42 | 2.91 | 2.91 |
| 252.27 | 2.77 | 2.77 |
| 280.30 | 2.26 | 2.26 |
| 486.48 | 3.48 | 3.48 |
| 582.48 | 2.89 | 2.89 |
| 231.32 | 2.25 | 2.25 |
| 603.23 | ||
| 240.26 | 2.04 | 2.04 |
| 368.39 | 3.07 | 3.07 |
| 372.24 | 2.52 | 2.52 |
| 434.52 | 4.10 | 4.10 |
| 358.46 | 3.74 | 3.74 |
| 323.30 | 2.82 | 2.82 |
| 246.29 | 2.44 | 2.44 |
| 328.35 | 2.12 | 2.12 |
| 393.19 | 2.34 | 2.34 |
| 274.28 | 1.96 | 1.96 |
| 326.30 | 3.15 | 3.15 |
| 257.32 | 2.15 | 2.15 |
| 325.36 | 2.60 | 2.60 |
| 278.17 | 0.72 | 0.72 |
| 270.29 | 2.17 | 2.17 |
| 335.39 | 1.75 | 1.75 |
| 288.32 | 3.18 | 3.18 |
| 288.35 | 3.08 | 3.08 |
| 438.96 | 3.11 | 3.11 |
| 262.27 | 2.26 | 2.26 |
| 512.97 | 2.92 | 2.92 |
| 492.15 | 6.80 | 6.80 |
| 513.54 | 4.16 | 4.16 |
| 250.21 | -0.24 | -0.24 |
| 415.43 | 0.97 | 0.97 |
| 176.12 | -2.81 | -2.81 |
| 330.34 | 3.07 | 3.07 |
| 359.36 | 4.40 | 4.40 |
| 194.19 | 0.15 | 0.15 |
| 359.36 | 4.40 | 4.40 |
| 180.16 | 0.66 | 0.66 |
| 353.14 | 1.42 | 1.42 |
| 298.41 | 2.88 | 2.88 |
| 230.09 | -0.77 | -0.77 |
| 210.22 | 0.39 | 0.39 |
| 403.41 | 2.52 | 2.52 |
| 350.22 | ||
| 417.46 | 2.56 | 2.56 |
| 315.35 | 3.54 | 3.54 |
| 206.16 | 0.03 | 0.03 |
| 414.37 | 4.53 | 4.53 |
| 224.17 | 0.08 | 0.08 |
| 421.54 | 5.47 | 5.47 |
| 300.27 | 1.08 | 1.08 |
| 239.25 | 1.37 | 1.37 |
| 315.35 | 3.54 | 3.54 |
| 566.68 | 4.10 | 4.10 |
| 365.38 | 4.03 | 4.03 |
| 240.26 | 3.70 | 3.70 |
| 308.34 | 4.25 | 4.25 |
| 360.35 | 3.62 | 3.62 |
| 283.33 | 4.21 | 4.21 |
| 312.24 | 0.24 | 0.24 |
| 182.17 | 0.88 | 0.88 |
| 168.15 | 0.66 | 0.66 |
| 262.34 | 3.17 | 3.17 |
| 212.14 | -0.71 | -0.71 |
| 560.84 | 2.60 | 2.60 |
| 209.16 | 0.46 | 0.46 |
| 246.22 | 1.45 | 1.45 |
| 339.40 | 2.51 | 2.51 |
| 272.26 | 1.96 | 1.96 |
| 284.27 | 2.56 | 2.56 |
| 271.32 | 2.42 | 2.42 |
| 263.30 | 3.86 | 3.86 |
| 543.00 | 2.92 | 2.92 |
| 434.41 | 3.08 | 3.08 |
| 250.66 | 2.72 | 2.72 |
| 279.34 | 4.31 | 4.31 |
| 430.50 | 5.16 | 5.16 |
| 410.81 | 3.73 | 3.73 |
| 392.84 | 3.56 | 3.56 |
| 464.43 | 1.80 | 1.80 |
| 406.39 | 3.09 | 3.09 |
| 248.67 | 2.28 | 2.28 |
| 471.47 | -0.54 | -0.54 |
| 545.53 | ||
| 371.37 | 3.29 | 3.29 |
| 403.41 | 4.00 | 4.00 |
| 333.26 | 0.78 | 0.78 |
| 343.36 | 2.48 | 2.48 |
| 288.33 | 2.55 | 2.55 |
| 382.38 | 2.03 | 2.03 |
| 422.85 | 4.07 | 4.07 |
| 359.18 | 3.66 | 3.66 |
| 275.33 | 3.34 | 3.34 |
| 427.37 | 1.73 | 1.73 |
| 403.44 | 3.43 | 3.43 |
| 278.32 | 3.08 | 3.08 |
| 222.15 | 0.47 | 0.47 |
| 249.30 | 1.70 | 1.70 |
| 302.29 | 2.45 | 2.45 |
| 353.18 | 2.04 | 2.04 |
| 268.32 | 1.91 | 1.91 |
| 277.24 | -0.04 | -0.04 |
| 269.30 | 3.28 | 3.28 |
| 259.33 | 3.64 | 3.64 |
| 392.85 | 4.14 | 4.14 |
| 327.38 | 2.57 | 2.57 |
| 605.67 | 4.14 | 4.14 |
| 389.41 | 3.17 | 3.17 |
| 411.44 | 2.20 | 2.20 |
| 472.44 | 2.95 | 2.95 |
| 272.26 | 2.08 | 2.08 |
| 331.28 | 1.87 | 1.87 |
| 246.23 | 0.85 | 0.85 |
| 450.47 | 2.53 | 2.53 |
| 481.53 | 5.84 | 5.84 |
| 297.15 | 2.79 | 2.79 |
| 312.33 | 4.29 | 4.29 |
| 330.30 | 1.18 | 1.18 |
| 530.61 | 5.49 | 5.49 |
| 419.33 | 5.58 | 5.58 |
| 301.26 | 3.00 | 3.00 |
| 383.43 | 2.74 | 2.74 |
| 452.26 | 4.45 | 4.45 |
| 879.86 | 6.39 | 6.39 |
| 413.38 | 3.17 | 3.17 |