Basic Information
ID: ALA2354292
Type: Functional
Description: PubChem BioAssay. Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA2354292
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 414.41 | 2.41 | 2.41 |
| 301.33 | 3.03 | 3.03 |
| 264.32 | 2.47 | 2.47 |
| 399.44 | 2.87 | 2.87 |
| 254.24 | 2.87 | 2.87 |
| 427.45 | 2.68 | 2.68 |
| 507.49 | 2.69 | 2.69 |
| 429.47 | 3.48 | 3.48 |
| 280.36 | 1.96 | 1.96 |
| 282.30 | 3.48 | 3.48 |
| 373.47 | 3.41 | 3.41 |
| 327.18 | 4.09 | 4.09 |
| 410.51 | 1.52 | 1.52 |
| 300.27 | 2.59 | 2.59 |
| 360.32 | 2.60 | 2.60 |
| 414.41 | 2.41 | 2.41 |
| 371.43 | 2.95 | 2.95 |
| 401.48 | 3.28 | 3.28 |
| 254.36 | 3.94 | 3.94 |
| 909.07 | 3.99 | 3.99 |
| 380.35 | 3.63 | 3.63 |
| 285.27 | 3.36 | 3.36 |
| 923.05 | 3.52 | 3.52 |
| 468.54 | 3.50 | 3.50 |
| 297.31 | 3.05 | 3.05 |
| 257.29 | 2.96 | 2.96 |
| 219.67 | 0.35 | 0.35 |
| 248.31 | 1.86 | 1.86 |
| 340.35 | 2.76 | 2.76 |
| 279.30 | 2.79 | 2.79 |
| 295.30 | 3.00 | 3.00 |
| 341.44 | 3.47 | 3.47 |
| 348.41 | 3.08 | 3.08 |
| 325.33 | 1.76 | 1.76 |
| 458.97 | 4.21 | 4.21 |
| 284.71 | 2.93 | 2.93 |
| 218.21 | 1.94 | 1.94 |
| 375.45 | 2.60 | 2.60 |
| 322.46 | 3.31 | 3.31 |
| 333.39 | 4.73 | 4.73 |
| 272.33 | 3.76 | 3.76 |
| 343.86 | 3.15 | 3.15 |
| 296.33 | 2.70 | 2.70 |
| 283.36 | 3.56 | 3.56 |
| 337.47 | 3.95 | 3.95 |
| 332.43 | 2.86 | 2.86 |
| 422.53 | 2.58 | 2.58 |
| 440.57 | 4.27 | 4.27 |
| 410.54 | 4.04 | 4.04 |
| 312.37 | 3.20 | 3.20 |
| 553.14 | 5.49 | 5.49 |
| 415.45 | 5.10 | 5.10 |
| 280.37 | 3.84 | 3.84 |
| 273.30 | 4.73 | 4.73 |
| 353.40 | 2.80 | 2.80 |
| 431.51 | 1.91 | 1.91 |
| 284.33 | 3.68 | 3.68 |
| 426.52 | 4.46 | 4.46 |
| 346.18 | 3.99 | 3.99 |
| 259.35 | 3.32 | 3.32 |
| 287.75 | 3.29 | 3.29 |
| 364.52 | 3.62 | 3.62 |
| 327.17 | 3.12 | 3.12 |
| 307.39 | 4.29 | 4.29 |
| 396.45 | 2.39 | 2.39 |
| 292.34 | 3.80 | 3.80 |
| 374.44 | 3.29 | 3.29 |
| 404.87 | 4.70 | 4.70 |
| 266.35 | 3.45 | 3.45 |
| 434.50 | 2.81 | 2.81 |
| 315.37 | 3.64 | 3.64 |
| 377.44 | 3.38 | 3.38 |
| 291.33 | 2.64 | 2.64 |
| 415.49 | 3.21 | 3.21 |
| 390.44 | 3.00 | 3.00 |
| 282.34 | 2.90 | 2.90 |
| 403.49 | 2.91 | 2.91 |
| 275.74 | 2.81 | 2.81 |
| 367.45 | 3.56 | 3.56 |
| 352.44 | 2.98 | 2.98 |
| 363.42 | 2.95 | 2.95 |
| 272.30 | 1.59 | 1.59 |
| 451.59 | 5.26 | 5.26 |
| 282.30 | 3.48 | 3.48 |
| 512.52 | 5.04 | 5.04 |
| 331.20 | 3.14 | 3.14 |
| 357.21 | 4.01 | 4.01 |
| 280.80 | 4.57 | 4.57 |
| 346.18 | 3.12 | 3.12 |
| 293.43 | 3.17 | 3.17 |
| 348.41 | 6.22 | 6.22 |
| 288.35 | 3.50 | 3.50 |
| 267.29 | 2.37 | 2.37 |
| 421.50 | 3.92 | 3.92 |
| 474.03 | 4.15 | 4.15 |
| 339.42 | 3.35 | 3.35 |
| 344.46 | 3.76 | 3.76 |
| 375.47 | 2.58 | 2.58 |
| 256.30 | 2.89 | 2.89 |
| 437.93 | 3.57 | 3.57 |
| 307.34 | 0.71 | 0.71 |
| 273.31 | 3.29 | 3.29 |
| 296.28 | 2.52 | 2.52 |
| 302.38 | 4.24 | 4.24 |
| 255.28 | 1.97 | 1.97 |
| 256.28 | 3.46 | 3.46 |
| 301.33 | 3.06 | 3.06 |
| 300.39 | 3.43 | 3.43 |
| 402.48 | 3.80 | 3.80 |
| 289.33 | 2.66 | 2.66 |
| 438.53 | 4.17 | 4.17 |
| 292.36 | 2.41 | 2.41 |
| 244.21 | -3.17 | -3.17 |
| 481.62 | 4.03 | 4.03 |
| 473.55 | 3.92 | 3.92 |
| 312.33 | 1.84 | 1.84 |
| 496.36 | 4.94 | 4.94 |
| 298.37 | 3.08 | 3.08 |
| 318.40 | 2.10 | 2.10 |
| 303.29 | 2.61 | 2.61 |
| 361.42 | 1.66 | 1.66 |
| 368.46 | 4.35 | 4.35 |
| 306.75 | 4.34 | 4.34 |
| 422.53 | 2.53 | 2.53 |
| 325.42 | 5.47 | 5.47 |
| 320.37 | 2.22 | 2.22 |
| 265.76 | 3.76 | 3.76 |
| 376.57 | 4.75 | 4.75 |
| 438.60 | 3.55 | 3.55 |
| 387.44 | 3.31 | 3.31 |
| 528.07 | 3.35 | 3.35 |
| 390.37 | 2.94 | 2.94 |
| 277.75 | 3.52 | 3.52 |
| 346.45 | 3.36 | 3.36 |
| 298.37 | 3.74 | 3.74 |
| 259.38 | 4.42 | 4.42 |
| 428.89 | 2.09 | 2.09 |
| 263.23 | 2.08 | 2.08 |
| 308.43 | 2.85 | 2.85 |
| 309.43 | 2.64 | 2.64 |
| 251.35 | 4.78 | 4.78 |
| 320.18 | 5.23 | 5.23 |
| 436.54 | 3.15 | 3.15 |
| 306.70 | 2.79 | 2.79 |
| 365.48 | 3.37 | 3.37 |
| 243.33 | 3.87 | 3.87 |
| 388.14 | 4.35 | 4.35 |
| 294.31 | 3.22 | 3.22 |
| 298.29 | 3.95 | 3.95 |
| 265.32 | 3.15 | 3.15 |
| 283.35 | 3.80 | 3.80 |
| 422.53 | 2.96 | 2.96 |
| 257.32 | 2.15 | 2.15 |
| 425.46 | 3.09 | 3.09 |
| 249.22 | 3.37 | 3.37 |
| 308.82 | 4.57 | 4.57 |
| 231.32 | 2.25 | 2.25 |
| 307.78 | 3.56 | 3.56 |
| 321.40 | 3.96 | 3.96 |
| 345.45 | 3.84 | 3.84 |
| 362.45 | 1.59 | 1.59 |
| 484.02 | 5.23 | 5.23 |
| 224.26 | 2.89 | 2.89 |
| 360.41 | 3.94 | 3.94 |
| 391.45 | 3.89 | 3.89 |
| 337.36 | 4.00 | 4.00 |
| 290.34 | 3.49 | 3.49 |
| 433.55 | 4.94 | 4.94 |
| 309.36 | 3.72 | 3.72 |
| 269.33 | 2.86 | 2.86 |
| 274.30 | 3.15 | 3.15 |
| 292.40 | 1.96 | 1.96 |
| 445.54 | 4.19 | 4.19 |
| 524.60 | 3.54 | 3.54 |
| 326.35 | 2.18 | 2.18 |
| 531.63 | 3.53 | 3.53 |
| 328.37 | 3.01 | 3.01 |
| 299.36 | 3.86 | 3.86 |
| 385.42 | 2.57 | 2.57 |
| 785.11 | 5.19 | 5.19 |
| 270.34 | 4.89 | 4.89 |
| 327.37 | 2.80 | 2.80 |
| 367.45 | 3.51 | 3.51 |
| 447.60 | 3.85 | 3.85 |
| 291.37 | 3.05 | 3.05 |
| 449.53 | 4.91 | 4.91 |
| 364.49 | 5.47 | 5.47 |
| 677.33 | 2.49 | 2.49 |
| 429.47 | 2.97 | 2.97 |
| 414.57 | 3.99 | 3.99 |
| 461.51 | 4.17 | 4.17 |
| 923.05 | 3.52 | 3.52 |
| 306.37 | 3.33 | 3.33 |
| 473.61 | 4.55 | 4.55 |
| 259.26 | 2.33 | 2.33 |
| 403.44 | 4.26 | 4.26 |
| 428.46 | 4.67 | 4.67 |
| 268.74 | 4.55 | 4.55 |
| 387.44 | 3.33 | 3.33 |
| 417.47 | 4.57 | 4.57 |
| 264.32 | 3.91 | 3.91 |
| 293.37 | 3.73 | 3.73 |
| 352.23 | 2.96 | 2.96 |
| 397.70 | 6.01 | 6.01 |
| 324.41 | 5.19 | 5.19 |
| 433.46 | 4.27 | 4.27 |
| 265.27 | 3.73 | 3.73 |
| 334.79 | 2.67 | 2.67 |
| 264.32 | 3.91 | 3.91 |
| 258.35 | 2.01 | 2.01 |
| 276.73 | 2.97 | 2.97 |
| 231.28 | 1.91 | 1.91 |
| 377.40 | 2.92 | 2.92 |
| 283.33 | 3.10 | 3.10 |
| 260.32 | 2.61 | 2.61 |
| 269.26 | 1.57 | 1.57 |
| 377.29 | 5.66 | 5.66 |
| 391.31 | 5.97 | 5.97 |
| 351.41 | 2.10 | 2.10 |
| 324.36 | 3.47 | 3.47 |
| 332.36 | 4.96 | 4.96 |
| 372.42 | 3.57 | 3.57 |
| 312.39 | 3.39 | 3.39 |
| 433.46 | 4.27 | 4.27 |
| 434.99 | 4.33 | 4.33 |
| 403.73 | 6.07 | 6.07 |
| 385.42 | 3.16 | 3.16 |
| 328.44 | 3.88 | 3.88 |
| 377.29 | 5.66 | 5.66 |
| 330.34 | 2.98 | 2.98 |
| 366.40 | 3.04 | 3.04 |
| 507.63 | 2.92 | 2.92 |
| 338.39 | 3.02 | 3.02 |
| 281.27 | 3.21 | 3.21 |
| 996.29 | 4.94 | 4.94 |
| 283.29 | 2.99 | 2.99 |
| 414.53 | 3.20 | 3.20 |
| 359.23 | 3.05 | 3.05 |
| 251.29 | 3.58 | 3.58 |
| 353.30 | 3.24 | 3.24 |
| 232.28 | 2.43 | 2.43 |
| 285.32 | 2.66 | 2.66 |
| 259.33 | 2.48 | 2.48 |
| 291.31 | 3.41 | 3.41 |
| 266.31 | 2.31 | 2.31 |
| 336.21 | 2.14 | 2.14 |
| 298.34 | 3.07 | 3.07 |
| 265.11 | 3.05 | 3.05 |
| 419.41 | 3.96 | 3.96 |