Basic Information
ID: ALA2354303
Type: Functional
Description: PubChem BioAssay. Dose-response confirmation of inhibitors of cullin neddylation in a TR-FRET assay. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA2354303
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 177.16 | -0.20 | -0.20 |
| 300.32 | 3.46 | 3.46 |
| 350.38 | 3.30 | 3.30 |
| 292.36 | 2.52 | 2.52 |
| 394.43 | 2.83 | 2.83 |
| 412.53 | 3.48 | 3.48 |
| 506.57 | 3.37 | 3.37 |
| 490.43 | 2.92 | 2.92 |
| 224.25 | -0.26 | -0.26 |
| 365.24 | -1.86 | -1.86 |
| 472.55 | 2.08 | 2.08 |
| 414.51 | 4.69 | 4.69 |
| 523.50 | 4.84 | 4.84 |
| 429.51 | 3.99 | 3.99 |
| 284.32 | 1.98 | 1.98 |
| 472.34 | 3.35 | 3.35 |
| 291.39 | 3.95 | 3.95 |
| 418.52 | 3.18 | 3.18 |
| 475.89 | 3.33 | 3.33 |
| 268.27 | 3.17 | 3.17 |
| 366.37 | 2.83 | 2.83 |
| 427.48 | 4.62 | 4.62 |
| 457.02 | 4.34 | 4.34 |
| 356.40 | 3.31 | 3.31 |
| 386.33 | 4.06 | 4.06 |
| 364.41 | 2.49 | 2.49 |
| 469.54 | 4.59 | 4.59 |
| 245.26 | 1.89 | 1.89 |
| 243.31 | 3.08 | 3.08 |
| 350.40 | 3.72 | 3.72 |
| 418.49 | 4.95 | 4.95 |
| 351.45 | 2.56 | 2.56 |
| 211.17 | 0.36 | 0.36 |
| 305.81 | 4.33 | 4.33 |
| 362.39 | 3.09 | 3.09 |
| 222.25 | 3.00 | 3.00 |
| 539.61 | 2.52 | 2.52 |
| 532.55 | 2.17 | 2.17 |
| 378.35 | 4.07 | 4.07 |
| 389.43 | 1.87 | 1.87 |
| 345.40 | 2.90 | 2.90 |
| 312.37 | 3.86 | 3.86 |
| 319.74 | 3.33 | 3.33 |
| 309.39 | 3.13 | 3.13 |
| 263.26 | 2.50 | 2.50 |
| 436.52 | 4.30 | 4.30 |
| 212.25 | 1.95 | 1.95 |
| 287.32 | 1.61 | 1.61 |
| 304.25 | 1.54 | 1.54 |
| 469.58 | 6.25 | 6.25 |
| 391.43 | 3.33 | 3.33 |
| 430.51 | 3.14 | 3.14 |
| 303.27 | 1.85 | 1.85 |
| 203.24 | 2.60 | 2.60 |
| 309.32 | 3.47 | 3.47 |
| 340.43 | 3.04 | 3.04 |
| 327.41 | 2.89 | 2.89 |
| 257.29 | 2.64 | 2.64 |
| 212.28 | 3.36 | 3.36 |
| 489.96 | 5.28 | 5.28 |
| 352.35 | 1.35 | 1.35 |
| 402.50 | 3.48 | 3.48 |
| 387.44 | 3.98 | 3.98 |
| 240.26 | 2.89 | 2.89 |
| 329.32 | 4.74 | 4.74 |
| 382.40 | 3.36 | 3.36 |
| 226.23 | 3.36 | 3.36 |
| 417.42 | 3.44 | 3.44 |
| 339.40 | 2.35 | 2.35 |
| 315.72 | 3.35 | 3.35 |
| 319.36 | 3.14 | 3.14 |
| 434.50 | 1.98 | 1.98 |
| 299.37 | 3.35 | 3.35 |
| 476.51 | 1.38 | 1.38 |
| 320.40 | 3.30 | 3.30 |
| 472.55 | 1.55 | 1.55 |
| 531.59 | 3.24 | 3.24 |
| 367.84 | 3.00 | 3.00 |
| 458.86 | 1.82 | 1.82 |
| 434.54 | 2.47 | 2.47 |
| 451.52 | 4.35 | 4.35 |
| 357.44 | 3.59 | 3.59 |
| 337.38 | 2.60 | 2.60 |
| 342.42 | 2.48 | 2.48 |
| 333.39 | 3.37 | 3.37 |
| 359.45 | 4.86 | 4.86 |
| 418.38 | 3.32 | 3.32 |
| 210.24 | 2.10 | 2.10 |
| 294.31 | 2.70 | 2.70 |
| 434.54 | 3.17 | 3.17 |
| 323.35 | 3.25 | 3.25 |
| 380.36 | 2.57 | 2.57 |
| 347.40 | 0.24 | 0.24 |
| 376.37 | 2.83 | 2.83 |
| 335.36 | 3.32 | 3.32 |
| 399.49 | 4.47 | 4.47 |
| 481.64 | 4.84 | 4.84 |
| 483.55 | 2.87 | 2.87 |
| 318.38 | 3.47 | 3.47 |
| 364.43 | 3.76 | 3.76 |
| 422.53 | 4.79 | 4.79 |
| 476.60 | 5.29 | 5.29 |
| 265.31 | 3.39 | 3.39 |
| 501.54 | 2.55 | 2.55 |
| 259.33 | 3.06 | 3.06 |
| 303.32 | 3.23 | 3.23 |
| 374.44 | 4.34 | 4.34 |
| 400.46 | 3.89 | 3.89 |
| 492.53 | 3.74 | 3.74 |
| 405.41 | 2.51 | 2.51 |
| 510.39 | 3.79 | 3.79 |
| 344.44 | 2.61 | 2.61 |
| 420.51 | 4.94 | 4.94 |
| 428.50 | 2.06 | 2.06 |
| 434.52 | 3.19 | 3.19 |
| 276.37 | 2.96 | 2.96 |
| 406.44 | 3.98 | 3.98 |
| 350.42 | 2.66 | 2.66 |
| 280.28 | 2.15 | 2.15 |
| 365.39 | 2.14 | 2.14 |
| 375.38 | 1.57 | 1.57 |
| 379.42 | 3.24 | 3.24 |
| 349.47 | 4.59 | 4.59 |
| 454.55 | 3.52 | 3.52 |
| 343.34 | 2.91 | 2.91 |
| 324.29 | 3.03 | 3.03 |
| 323.35 | 1.95 | 1.95 |
| 236.27 | 2.60 | 2.60 |
| 311.38 | 2.54 | 2.54 |
| 435.48 | 1.29 | 1.29 |
| 317.35 | 2.50 | 2.50 |
| 330.43 | 4.83 | 4.83 |
| 295.27 | 2.77 | 2.77 |
| 341.44 | 3.23 | 3.23 |
| 370.41 | 2.80 | 2.80 |
| 445.52 | 3.33 | 3.33 |
| 203.24 | 3.88 | 3.88 |
| 382.44 | 3.39 | 3.39 |
| 340.47 | 4.64 | 4.64 |
| 402.49 | 3.33 | 3.33 |
| 316.45 | 3.13 | 3.13 |
| 450.34 | 4.24 | 4.24 |
| 197.19 | 1.72 | 1.72 |
| 422.53 | 4.74 | 4.74 |
| 445.52 | 3.33 | 3.33 |
| 400.29 | 2.15 | 2.15 |
| 252.28 | 2.35 | 2.35 |
| 326.35 | 3.38 | 3.38 |
| 256.30 | 2.92 | 2.92 |
| 389.50 | 3.66 | 3.66 |
| 436.48 | 4.09 | 4.09 |
| 443.53 | 4.52 | 4.52 |
| 358.46 | 3.14 | 3.14 |
| 211.22 | -0.94 | -0.94 |
| 475.51 | 2.39 | 2.39 |
| 415.45 | 3.87 | 3.87 |
| 308.77 | 4.52 | 4.52 |
| 259.35 | 2.39 | 2.39 |
| 388.49 | 2.83 | 2.83 |
| 352.23 | 5.16 | 5.16 |
| 485.52 | 4.01 | 4.01 |
| 414.53 | 3.19 | 3.19 |
| 221.07 | 1.90 | 1.90 |
| 185.19 | 1.99 | 1.99 |
| 368.37 | 3.44 | 3.44 |
| 414.33 | 2.76 | 2.76 |
| 423.52 | 5.27 | 5.27 |
| 221.26 | 2.90 | 2.90 |
| 400.29 | 2.67 | 2.67 |
| 367.45 | 2.67 | 2.67 |
| 460.54 | 5.30 | 5.30 |
| 438.53 | 4.50 | 4.50 |
| 442.11 | 3.62 | 3.62 |
| 383.40 | 2.97 | 2.97 |
| 386.40 | 2.73 | 2.73 |
| 325.41 | 2.72 | 2.72 |
| 447.45 | 1.61 | 1.61 |
| 307.40 | 3.49 | 3.49 |
| 307.40 | 3.01 | 3.01 |
| 358.47 | 2.47 | 2.47 |
| 423.49 | 3.57 | 3.57 |
| 352.51 | 3.70 | 3.70 |
| 446.31 | 3.25 | 3.25 |
| 431.45 | 2.54 | 2.54 |
| 427.48 | 4.78 | 4.78 |
| 468.33 | 2.14 | 2.14 |
| 383.40 | 2.97 | 2.97 |
| 491.53 | 3.70 | 3.70 |
| 234.29 | 0.86 | 0.86 |
| 336.40 | 2.03 | 2.03 |
| 369.47 | 3.24 | 3.24 |
| 351.40 | 4.14 | 4.14 |
| 327.38 | 2.29 | 2.29 |
| 343.35 | 2.65 | 2.65 |
| 311.39 | 2.59 | 2.59 |
| 442.50 | 3.71 | 3.71 |
| 275.40 | 3.03 | 3.03 |
| 297.36 | 2.28 | 2.28 |
| 408.88 | 3.11 | 3.11 |
| 335.41 | 2.71 | 2.71 |
| 367.41 | 3.35 | 3.35 |
| 230.27 | 1.09 | 1.09 |
| 462.50 | 3.86 | 3.86 |
| 448.42 | -1.86 | -1.86 |