Assay Report Card

Basic Information

ID: ALA2354305

Type: Functional

Description: PubChem BioAssay. Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis. (Class of assay: confirmatory)

Activity Charts

Bioactivity

Activity Types for Assay ALA2354305

IC50

Total(174)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
228.25	2.98	2.98
367.47	3.12	3.12
222.24	3.46	3.46
270.34	4.89	4.89
252.27	3.31	3.31
467.66	4.35	4.35
302.38	4.43	4.43
401.49	2.55	2.55
371.86	2.66	2.66
261.30	2.77	2.77
260.25	0.69	0.69
369.51	1.64	1.64
410.47	3.14	3.14
432.59	3.90	3.90
393.87	2.55	2.55
397.38	1.87	1.87
337.36	3.91	3.91
250.31	2.89	2.89
337.31	1.59	1.59
238.29	3.69	3.69
348.22	4.73	4.73
310.36	2.91	2.91
407.00	2.60	2.60
276.32	1.72	1.72
351.21	4.03	4.03
398.42	3.61	3.61
287.32	2.10	2.10
439.47	2.20	2.20
513.65	3.19	3.19
265.29	2.39	2.39
217.22	2.25	2.25
351.82	1.45	1.45
379.49	4.86	4.86
320.35	2.85	2.85
410.45	0.63	0.63
262.25	1.00	1.00
216.27	2.39	2.39
280.33	3.68	3.68
365.39	3.41	3.41
214.29	3.30	3.30
256.26	2.86	2.86
200.67	0.54	0.54
350.25	3.19	3.19
376.36	4.59	4.59
302.38	4.94	4.94
487.55	4.22	4.22
399.90	3.92	3.92
359.38	2.12	2.12
228.27	0.55	0.55
418.50	3.18	3.18
471.48	3.56	3.56
330.84	4.17	4.17
469.58	6.25	6.25
537.97	7.24	7.24
373.43	2.79	2.79
224.26	3.39	3.39
304.82	3.44	3.44
322.37	2.23	2.23
230.65	2.98	2.98
278.30	2.37	2.37
358.43	1.83	1.83
389.89	5.33	5.33
317.37	1.72	1.72
318.83	4.13	4.13
397.43	3.34	3.34
259.70	2.34	2.34
444.51	2.10	2.10
280.32	3.72	3.72
448.50	2.60	2.60
249.32	3.47	3.47
306.33	2.69	2.69
260.30	4.35	4.35
197.24	1.82	1.82
429.48	3.86	3.86
232.24	1.18	1.18
285.30	2.64	2.64
213.24	2.61	2.61
404.51	4.94	4.94
254.29	2.40	2.40
345.40	3.36	3.36
335.40	4.62	4.62
282.30	1.70	1.70
439.57	3.66	3.66
450.50	3.37	3.37
367.49	4.01	4.01
310.31	2.13	2.13
407.52	2.56	2.56
450.50	3.04	3.04
357.48	2.35	2.35
432.48	5.11	5.11
497.62	3.77	3.77
273.32	2.36	2.36
420.56	3.64	3.64
450.45	3.66	3.66
362.45	5.93	5.93
363.39	1.83	1.83
309.42	4.37	4.37
367.40	2.64	2.64
350.45	3.60	3.60
232.24	1.26	1.26
363.46	4.26	4.26
279.30	4.02	4.02
238.29	2.62	2.62
297.42	4.04	4.04
237.72	2.94	2.94
315.38	2.06	2.06
233.22	1.16	1.16
298.35	2.62	2.62
445.47	3.90	3.90
424.49	1.94	1.94
497.08	5.36	5.36
377.42	1.73	1.73
211.27	2.58	2.58
321.36	4.20	4.20
225.25	2.67	2.67
433.51	6.23	6.23
279.36	1.68	1.68
376.28	3.83	3.83
395.20	4.05	4.05
423.47	2.12	2.12
444.51	5.78	5.78
261.33	3.14	3.14
429.97	4.46	4.46
328.32	3.62	3.62
290.32	2.40	2.40
253.31	2.97	2.97
393.49	4.08	4.08
261.28	1.53	1.53
421.45	3.07	3.07
262.29	1.31	1.31
448.56	4.21	4.21
419.53	3.61	3.61
376.44	4.47	4.47
411.45	4.55	4.55
397.43	4.15	4.15
297.32	1.77	1.77
471.51
417.47	2.83	2.83
388.46	2.02	2.02
357.41	0.22	0.22
252.73	3.64	3.64
252.32	2.68	2.68
341.41	1.99	1.99
267.29	2.64	2.64
236.27	3.10	3.10
287.32	2.10	2.10
327.38	4.13	4.13
295.34	3.79	3.79
410.47	2.55	2.55
245.31	2.78	2.78
284.32	2.46	2.46
407.48	4.41	4.41
393.51	3.89	3.89
467.55	3.39	3.39
206.24	2.39	2.39
406.87	2.57	2.57
322.32	3.79	3.79
283.38	1.94	1.94
221.26	2.90	2.90
201.23	1.60	1.60
433.51	4.16	4.16
367.41	1.55	1.55
374.40	3.81	3.81
342.35	5.76	5.76
369.38	1.03	1.03
259.30	2.40	2.40
226.24	1.05	1.05
329.43	4.87	4.87
384.26	4.80	4.80
300.75	2.67	2.67
328.38	4.19	4.19
230.27	1.12	1.12
247.30	4.30	4.30
294.31	2.77	2.77