ID: ALA2363028
Type: Functional
Description: MMV: Toxicity @ 5 uM to 4-5 Schistosoma mansoni adult males after 72 h on a scale of 0 (none) - 4 (most). Includes short descriptors of effects as judged visually (PMID:19597541). Only those Malaria box 'drug-like' cpds yielding the most severe phenotypes vs. somules were tested. Caffrey group UCSF.
Organism: Schistosoma mansoni
Bioactivity
Activity Types for Assay ALA2363028
Toxicity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
291.40 | 3.88 | 3.88 |
347.26 | 3.78 | 3.78 |
298.77 | 4.95 | 4.95 |
367.28 | 3.70 | 3.70 |
249.75 | 2.91 | 2.91 |
479.85 | 3.90 | 3.90 |
398.51 | 5.20 | 5.20 |
497.75 | 4.59 | 4.59 |
354.47 | 4.02 | 4.02 |
384.50 | 4.03 | 4.03 |
418.59 | 4.27 | 4.27 |
328.17 | 4.12 | 4.12 |
413.52 | 5.59 | 5.59 |
354.41 | 4.46 | 4.46 |
420.18 | 4.45 | 4.45 |
480.01 | 5.37 | 5.37 |
388.52 | 4.85 | 4.85 |
373.41 | 4.50 | 4.50 |
457.83 | 4.30 | 4.30 |
356.43 | 4.99 | 4.99 |
496.50 | 5.20 | 5.20 |
460.54 | 6.38 | 6.38 |
232.71 | 3.49 | 3.49 |
287.32 | 1.31 | 1.31 |
362.27 | 3.63 | 3.63 |
469.31 | 3.61 | 3.61 |
368.91 | 5.09 | 5.09 |
366.89 | 3.95 | 3.95 |
310.42 | 4.85 | 4.85 |
360.24 | 4.22 | 4.22 |
333.58 | 5.43 | 5.43 |
355.95 | 3.72 | 3.72 |
425.96 | 4.84 | 4.84 |
315.68 | 4.32 | 4.32 |
416.29 | 4.16 | 4.16 |
308.43 | 3.69 | 3.69 |
384.50 | 3.67 | 3.67 |
341.33 | 0.31 | 0.31 |
401.51 | 4.70 | 4.70 |
465.47 | 4.32 | 4.32 |