Basic Information
ID: ALA2378030
Type: Binding
Description: Inhibition of FCgamma receptor in human PBMC assessed as inhibition of opsonized RBC phagocytosis at 5 uM incubated for 1 hr prior to RBC addition measured after 2 hrs by monocyte monolayer assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: High affinity immunoglobulin gamma Fc receptor I(ALA5349)
Document: ALA2375223
Inhibition of FCgamma receptor in human PBMC assessed as inhibition of opsonized RBC phagocytosis at 5 uM incubated for 1 hr prior to RBC addition measured after 2 hrs by monocyte monolayer assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2378030
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 294.38 | 3.70 | 3.70 |
| 285.33 | 2.69 | 2.69 |
| 586.74 | 7.94 | 7.94 |
| 598.80 | 8.06 | 8.06 |
| 604.76 | 4.42 | 4.42 |
| 600.81 | 6.73 | 6.73 |
| 378.53 | 5.47 | 5.47 |