Basic Information
ID: ALA2378508
Type: Binding
Description: Inhibition of JAK2/1 in human T cells expressing CD3 assessed as inhibition of IFNgamma-stimulated STAT1 phosphorylation
Organism: Homo sapiens
Cell type: T-cell
Activity Charts
Bioactivity
Activity Types for Assay ALA2378508
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 312.38 | 1.54 | 1.54 |
| 306.37 | 3.47 | 3.47 |
| 380.45 | 1.96 | 1.96 |
| 464.48 | 1.75 | 1.75 |
| 461.91 | 2.87 | 2.87 |
| 462.90 | 2.27 | 2.27 |
| 446.45 | 1.75 | 1.75 |
| 458.48 | 1.62 | 1.62 |
| 480.89 | 2.40 | 2.40 |
| 432.42 | 1.51 | 1.51 |
| 450.41 | 1.65 | 1.65 |