Basic Information
ID: ALA2379081
Type: Binding
Description: Antagonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced intracellular Ca2+ elevation incubated for 5 mins prior to allyl isothiocyanate-stimulation by spectrofluorimetric analysis
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2379081
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 307.36 | 2.46 | 2.46 |
| 307.36 | 2.46 | 2.46 |
| 347.42 | 3.38 | 3.38 |
| 375.48 | 4.16 | 4.16 |
| 425.54 | 4.85 | 4.85 |
| 433.52 | 5.18 | 5.18 |
| 349.39 | 2.66 | 2.66 |
| 365.39 | 2.25 | 2.25 |
| 337.38 | 1.95 | 1.95 |
| 337.38 | 1.95 | 1.95 |
| 323.36 | 2.17 | 2.17 |
| 323.36 | 2.17 | 2.17 |
| 323.36 | 2.17 | 2.17 |
| 350.38 | 1.56 | 1.56 |
| 321.38 | 2.77 | 2.77 |
| 321.38 | 2.77 | 2.77 |
| 321.38 | 2.77 | 2.77 |
| 347.42 | 3.38 | 3.38 |
| 375.48 | 4.16 | 4.16 |
| 425.54 | 4.85 | 4.85 |
| 433.52 | 5.18 | 5.18 |
| 349.39 | 2.66 | 2.66 |
| 365.39 | 2.25 | 2.25 |
| 337.38 | 1.95 | 1.95 |
| 337.38 | 1.95 | 1.95 |
| 323.36 | 2.17 | 2.17 |
| 323.36 | 2.17 | 2.17 |
| 323.36 | 2.17 | 2.17 |
| 350.38 | 1.56 | 1.56 |
| 321.38 | 2.77 | 2.77 |
| 321.38 | 2.77 | 2.77 |
| 321.38 | 2.77 | 2.77 |