Basic Information
ID: ALA2379575
Type: Binding
Description: Inhibition of FAAH in Sprague-Dawley rat brain microsomes assessed as N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide conversion to 4-pyren-1-ylbutanoic acid preincubated for 10 mins measured after 45 mins by HPLC analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Brain
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA2379575
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 294.35 | 4.21 | 4.21 |
| 338.41 | 3.87 | 3.87 |
| 307.36 | 2.46 | 2.46 |
| 307.36 | 2.46 | 2.46 |
| 369.55 | 6.06 | 6.06 |
| 355.35 | 2.89 | 2.89 |
| 284.27 | 2.63 | 2.63 |
| 346.39 | 2.87 | 2.87 |
| 352.40 | 2.48 | 2.48 |
| 414.47 | 3.51 | 3.51 |
| 394.48 | 3.51 | 3.51 |
| 408.51 | 4.04 | 4.04 |
| 490.57 | 5.18 | 5.18 |
| 337.38 | 3.44 | 3.44 |
| 365.44 | 4.22 | 4.22 |
| 279.30 | 2.90 | 2.90 |
| 265.27 | 2.91 | 2.91 |
| 323.36 | 2.59 | 2.59 |
| 323.36 | 2.59 | 2.59 |
| 309.33 | 2.66 | 2.66 |
| 309.33 | 2.66 | 2.66 |
| 327.32 | 2.80 | 2.80 |
| 343.77 | 3.32 | 3.32 |
| 323.36 | 2.97 | 2.97 |
| 339.36 | 2.67 | 2.67 |
| 327.32 | 2.80 | 2.80 |
| 343.77 | 3.32 | 3.32 |
| 323.36 | 2.97 | 2.97 |
| 339.36 | 2.67 | 2.67 |
| 378.22 | 3.97 | 3.97 |
| 282.31 | 1.66 | 1.66 |
| 310.36 | 2.28 | 2.28 |
| 283.30 | 1.06 | 1.06 |
| 332.37 | 2.81 | 2.81 |
| 296.33 | 1.72 | 1.72 |
| 324.39 | 2.34 | 2.34 |