Basic Information
ID: ALA2379653
Type: Functional
Description: Inhibition of LPS-induced TNFalpha production in human PBMC at 5 ug/mL after overnight incubation relative to DMSO-treated control
Organism: Homo sapiens
Cell type: PBMC
Activity Charts
Bioactivity
Activity Types for Assay ALA2379653
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 510.08 | 6.56 | 6.56 |
| 489.67 | 6.21 | 6.21 |
| 407.61 | 6.05 | 6.05 |
| 375.54 | 5.71 | 5.71 |
| 349.46 | 4.36 | 4.36 |
| 383.90 | 5.02 | 5.02 |
| 363.49 | 4.67 | 4.67 |
| 363.49 | 4.75 | 4.75 |
| 397.93 | 5.41 | 5.41 |
| 377.51 | 5.06 | 5.06 |
| 379.49 | 4.97 | 4.97 |
| 413.93 | 5.63 | 5.63 |
| 393.51 | 5.28 | 5.28 |
| 393.51 | 5.36 | 5.36 |
| 427.96 | 6.02 | 6.02 |
| 407.54 | 5.67 | 5.67 |
| 412.95 | 4.77 | 4.77 |
| 447.39 | 5.42 | 5.42 |
| 426.97 | 5.07 | 5.07 |
| 426.97 | 5.16 | 5.16 |
| 461.42 | 5.81 | 5.81 |
| 441.00 | 5.46 | 5.46 |
| 385.51 | 3.78 | 3.78 |
| 419.96 | 4.43 | 4.43 |
| 399.54 | 4.09 | 4.09 |
| 399.54 | 4.17 | 4.17 |
| 433.99 | 4.82 | 4.82 |
| 413.57 | 4.48 | 4.48 |
| 461.61 | 5.51 | 5.51 |
| 496.06 | 6.17 | 6.17 |
| 475.64 | 5.82 | 5.82 |
| 475.64 | 5.90 | 5.90 |
| 250.33 | 4.44 | 4.44 |
| 264.35 | 4.75 | 4.75 |
| 284.77 | 5.10 | 5.10 |
| 329.22 | 5.21 | 5.21 |
| 296.42 | 5.16 | 5.16 |
| 318.32 | 5.46 | 5.46 |
| 284.77 | 5.10 | 5.10 |
| 329.22 | 5.21 | 5.21 |
| 318.32 | 5.46 | 5.46 |
| 284.77 | 5.10 | 5.10 |
| 329.22 | 5.21 | 5.21 |
| 318.32 | 5.46 | 5.46 |
| 395.96 | 5.98 | 5.98 |