Basic Information
ID: ALA2382556
Type: Binding
Description: Inhibition of MAO-B in mitochondria-enriched Sprague-Dawley rat liver fractions using p-tyramine as substrate incubated for 30 mins prior to substrate addition measured for 45 mins by amplex red reagent-based microplate fluorescence reader analysis
Format: BAO_0000252
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Subcellular Fraction: Mitochondria
Target: Monoamine oxidase B(ALA2993)
Document: ALA2380255
Inhibition of MAO-B in mitochondria-enriched Sprague-Dawley rat liver fractions using p-tyramine as substrate incubated for 30 mins prior to substrate addition measured for 45 mins by amplex red reagent-based microplate fluorescence reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2382556
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.78 | 1.79 | 1.79 |
| 187.29 | 2.18 | 2.18 |
| 302.35 | 2.37 | 2.37 |
| 519.03 | 4.52 | 4.52 |
| 519.03 | 4.52 | 4.52 |
| 519.03 | 4.52 | 4.52 |
| 338.43 | 3.64 | 3.64 |
| 310.38 | 3.23 | 3.23 |
| 340.40 | 3.24 | 3.24 |
| 484.58 | 3.87 | 3.87 |
| 282.32 | 2.91 | 2.91 |
| 338.43 | 3.93 | 3.93 |
| 358.85 | 4.27 | 4.27 |
| 403.30 | 4.38 | 4.38 |
| 358.85 | 4.27 | 4.27 |
| 330.43 | 3.68 | 3.68 |
| 330.43 | 3.68 | 3.68 |
| 358.49 | 4.30 | 4.30 |
| 379.27 | 4.53 | 4.53 |
| 328.37 | 3.37 | 3.37 |
| 389.27 | 3.99 | 3.99 |
| 346.80 | 3.33 | 3.33 |
| 338.39 | 3.32 | 3.32 |
| 342.81 | 3.96 | 3.96 |
| 336.37 | 2.66 | 2.66 |
| 324.40 | 3.62 | 3.62 |
| 354.43 | 3.63 | 3.63 |
| 358.85 | 4.27 | 4.27 |
| 393.30 | 4.92 | 4.92 |
| 322.39 | 3.70 | 3.70 |
| 352.42 | 3.71 | 3.71 |
| 356.83 | 4.35 | 4.35 |
| 391.28 | 5.01 | 5.01 |