Basic Information
ID: ALA2383532
Type: Functional
Description: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv infected in mouse J774.A1 cells at 1 MOI assessed as intracellular bacterial growth inhibition at 0.1 uM after 1 hr by luciferase reporter gene assay relative to control
Organism: Mycobacterium tuberculosis
Strain: H37Rv
Cell type: J774.A1
Activity Charts
Bioactivity
Activity Types for Assay ALA2383532
GI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 137.14 | -0.31 | -0.31 |
| 284.31 | 3.16 | 3.16 |
| 298.34 | 3.55 | 3.55 |
| 312.37 | 3.94 | 3.94 |
| 326.39 | 4.33 | 4.33 |
| 340.42 | 4.72 | 4.72 |
| 354.45 | 5.11 | 5.11 |
| 368.47 | 5.50 | 5.50 |
| 382.50 | 5.89 | 5.89 |
| 396.53 | 6.28 | 6.28 |
| 410.55 | 6.67 | 6.67 |
| 256.26 | 2.73 | 2.73 |
| 270.28 | 2.77 | 2.77 |