Basic Information
ID: ALA2383951
Type: Binding
Description: Inhibition of recombinant His-tagged SIRT3 (unknown origin) using Fluor de Lys acetylated KI179 as substrate at 200 uM incubated for 5 mins followed by enzyme addition measured after 1 hr by fluorescence assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 3(ALA4461)
Document: ALA2380241
Inhibition of recombinant His-tagged SIRT3 (unknown origin) using Fluor de Lys acetylated KI179 as substrate at 200 uM incubated for 5 mins followed by enzyme addition measured after 1 hr by fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2383951
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 351.41 | 1.85 | 1.85 |
| 397.41 | 2.01 | 2.01 |
| 380.81 | 5.47 | 5.47 |
| 387.84 | 2.93 | 2.93 |
| 443.53 | 1.55 | 1.55 |
| 365.52 | 4.46 | 4.46 |
| 399.97 | 5.30 | 5.30 |
| 392.33 | 5.03 | 5.03 |
| 364.47 | 3.83 | 3.83 |
| 413.39 | 2.70 | 2.70 |
| 442.51 | 2.22 | 2.22 |
| 417.43 | 3.47 | 3.47 |
| 367.42 | 2.28 | 2.28 |
| 357.24 | 5.99 | 5.99 |
| 362.82 | 5.33 | 5.33 |
| 417.40 | 0.05 | 0.05 |
| 397.26 | 5.98 | 5.98 |
| 358.37 | 5.29 | 5.29 |
| 362.82 | 5.33 | 5.33 |
| 407.27 | 5.44 | 5.44 |
| 342.40 | 4.98 | 4.98 |
| 342.40 | 4.98 | 4.98 |
| 358.40 | 4.68 | 4.68 |
| 397.26 | 5.98 | 5.98 |
| 374.83 | 5.80 | 5.80 |
| 342.78 | 2.87 | 2.87 |
| 403.46 | 0.81 | 0.81 |
| 397.86 | 2.43 | 2.43 |
| 373.19 | 4.63 | 4.63 |
| 437.85 | 3.81 | 3.81 |
| 369.48 | 3.85 | 3.85 |
| 397.26 | 5.98 | 5.98 |
| 362.82 | 5.33 | 5.33 |
| 441.71 | 6.09 | 6.09 |
| 380.40 | 2.05 | 2.05 |
| 380.81 | 5.47 | 5.47 |
| 398.80 | 5.61 | 5.61 |
| 442.32 | 2.10 | 2.10 |
| 407.47 | 2.18 | 2.18 |
| 367.42 | 2.59 | 2.59 |
| 437.85 | 3.81 | 3.81 |
| 529.30 | 3.76 | 3.76 |
| 346.36 | 4.82 | 4.82 |
| 380.40 | 3.27 | 3.27 |
| 381.43 | 1.85 | 1.85 |
| 408.46 | 1.57 | 1.57 |
| 366.44 | 3.41 | 3.41 |
| 351.39 | 3.81 | 3.81 |