Basic Information
ID: ALA2383983
Type: Functional
Description: Cytotoxicity against gefitinib-resistant human NCI-H1975 cells harboring EGFR L858R/T90M double mutant assessed as growth inhibition after 72 hrs by MTT assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA2383983
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 446.91 | 4.28 | 4.28 |
| 494.98 | 4.55 | 4.55 |
| 846.32 | 4.45 | 4.45 |
| 820.28 | 3.96 | 3.96 |
| 807.24 | 4.00 | 4.00 |
| 821.27 | 4.39 | 4.39 |
| 835.30 | 4.78 | 4.78 |
| 831.26 | 4.00 | 4.00 |
| 851.30 | 4.01 | 4.01 |
| 863.35 | 5.56 | 5.56 |
| 342.37 | 1.07 | 1.07 |
| 567.05 | 4.48 | 4.48 |
| 806.26 | 3.57 | 3.57 |
| 820.29 | 3.96 | 3.96 |
| 875.36 | 3.60 | 3.60 |