Assay Report Card

Basic Information

ID: ALA2384427

Type: Binding

Description: Agonist activity at REV-ERBalpha in human THP1 cells assessed as downregulation of LPS-stimulated IL-6 mRNA expression at 1 uM after 6 hrs by RT-qPCR analysis

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
355.414.504.50
421.356.476.47
357.414.394.39
353.884.874.87