Assay Report Card

Basic Information

ID: ALA2384430

Type: Binding

Description: Agonist activity at REV-ERBalpha in human U2OS cells assessed as suppression of BMAL1 expression at 20 uM after 40 hrs by luciferase reporter gene assay relative to DMSO-treated control

Organism: Homo sapiens

Cell type: U2OS

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
396.904.654.65
437.954.794.79
479.055.535.53
355.414.504.50
355.414.504.50
337.424.364.36
421.356.476.47
390.875.655.65
352.895.365.36
353.454.564.56
357.414.394.39
353.454.564.56
353.454.564.56
369.454.264.26
353.884.874.87
421.796.076.07
378.936.156.15
393.945.795.79