Assay Report Card

Basic Information

ID: ALA2387819

Type: Binding

Description: Inhibition of human EGFR extracellular domain/TIE2 intracellular domain transfected in mouse NIH/3T3 cells assessed as phosphotyrosine level preincubated for 60 mins followed by EGF stimulation by DELFIA assay

Organism: Homo sapiens

Cell type: NIH3T3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
497.534.444.44
476.495.285.28
497.534.444.44
476.495.285.28
483.544.804.80
474.955.665.66
509.406.316.31
472.525.455.45
484.565.325.32
509.544.754.75
488.505.595.59