Basic Information
ID: ALA2388759
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes assessed as midazolam-1'-hydroxylation by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2388759
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.45 | 4.15 | 4.15 |
| 405.43 | 3.47 | 3.47 |
| 438.53 | 5.15 | 5.15 |
| 334.38 | 2.92 | 2.92 |
| 358.39 | 3.13 | 3.13 |
| 368.82 | 3.58 | 3.58 |
| 386.81 | 3.72 | 3.72 |
| 384.44 | 4.08 | 4.08 |
| 402.43 | 4.22 | 4.22 |