Basic Information
ID: ALA2388856
Type: ADME
Description: Apparent permeability in MDCK cells expressing MDR1 at 3 uM after 60 mins by LC-MS/MS analysis
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK
Target: MDCK(ALA614068)
Document: ALA2385035
Apparent permeability in MDCK cells expressing MDR1 at 3 uM after 60 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2388856
Papp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.57 | 4.51 | 4.51 |
| 474.62 | 3.67 | 3.67 |
| 488.65 | 4.02 | 4.02 |
| 524.71 | 3.48 | 3.48 |
| 510.59 | 3.73 | 3.73 |
| 524.62 | 3.77 | 3.77 |
| 532.66 | 3.52 | 3.52 |
| 532.66 | 3.52 | 3.52 |
| 517.64 | 4.53 | 4.53 |
| 532.66 | 3.47 | 3.47 |
| 632.82 | 3.08 | 3.08 |
| 604.60 | 3.57 | 3.57 |
| 546.69 | 3.91 | 3.91 |
| 588.72 | 3.87 | 3.87 |
| 574.70 | 3.43 | 3.43 |
| 603.74 | 3.02 | 3.02 |
| 502.68 | 4.45 | 4.45 |
| 502.68 | 4.41 | 4.41 |
| 502.68 | 4.45 | 4.45 |
| 514.69 | 4.55 | 4.55 |
| 514.69 | 4.55 | 4.55 |
| 545.75 | 4.17 | 4.17 |
| 518.68 | 3.42 | 3.42 |
| 504.65 | 3.04 | 3.04 |
| 524.66 | 3.08 | 3.08 |
| 538.69 | 3.12 | 3.12 |
| 516.66 | 3.63 | 3.63 |
| 552.72 | 3.39 | 3.39 |
| 488.61 | 3.20 | 3.20 |
| 538.69 | 3.00 | 3.00 |
| 552.72 | 3.39 | 3.39 |
| 538.60 | 3.29 | 3.29 |
| 546.64 | 3.11 | 3.11 |
| 560.67 | 3.55 | 3.55 |
| 497.55 | 4.01 | 4.01 |
| 511.58 | 4.06 | 4.06 |
| 525.60 | 4.45 | 4.45 |
| 459.61 | 4.52 | 4.52 |
| 473.64 | 4.91 | 4.91 |
| 481.64 | 3.89 | 3.89 |
| 509.69 | 4.32 | 4.32 |
| 481.55 | 4.18 | 4.18 |
| 495.58 | 4.22 | 4.22 |
| 509.61 | 4.61 | 4.61 |
| 530.69 | 4.34 | 4.34 |
| 489.63 | 4.74 | 4.74 |
| 511.66 | 3.77 | 3.77 |
| 525.69 | 4.16 | 4.16 |
| 461.58 | 3.96 | 3.96 |