Basic Information
ID: ALA2388933
Type: Functional
Description: Antagonist activity at human prostanoid EP3 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced calcium flux after 60 mins by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2388933
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.37 | 3.94 | 3.94 |
| 398.46 | 4.39 | 4.39 |
| 452.43 | 5.10 | 5.10 |
| 436.87 | 4.87 | 4.87 |
| 416.45 | 4.15 | 4.15 |
| 405.43 | 3.47 | 3.47 |
| 430.48 | 4.54 | 4.54 |
| 438.53 | 5.15 | 5.15 |
| 472.97 | 5.81 | 5.81 |
| 334.38 | 2.92 | 2.92 |
| 364.40 | 2.93 | 2.93 |
| 376.46 | 4.05 | 4.05 |
| 340.42 | 3.19 | 3.19 |
| 358.39 | 3.13 | 3.13 |
| 368.82 | 3.58 | 3.58 |
| 386.81 | 3.72 | 3.72 |
| 421.25 | 4.37 | 4.37 |
| 384.44 | 4.08 | 4.08 |
| 418.88 | 4.73 | 4.73 |
| 402.43 | 4.22 | 4.22 |