Basic Information
ID: ALA2389981
Type: Binding
Description: Activation of TLR4 in C57BL/6 mouse BMDC cells assessed as AUC of IL6 release after 18 hrs by ELISA relative to N-cyclohexyl-2-(4-oxo-3-phenyl-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-ylthio)acetamide
Organism: Mus musculus
Strain: C57BL/6
Cell type: BMDC
Activity Charts
Bioactivity
Activity Types for Assay ALA2389981
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.54 | 4.55 | 4.55 |
| 434.52 | 3.62 | 3.62 |
| 444.49 | 4.74 | 4.74 |
| 471.59 | 4.40 | 4.40 |
| 489.60 | 3.37 | 3.37 |
| 433.54 | 2.83 | 2.83 |
| 1077.42 | ||
| 438.60 | 4.92 | 4.92 |
| 446.58 | 4.72 | 4.72 |
| 482.61 | 5.56 | 5.56 |
| 460.60 | 4.66 | 4.66 |
| 424.57 | 4.53 | 4.53 |
| 446.58 | 4.42 | 4.42 |
| 460.60 | 4.76 | 4.76 |
| 532.67 | 4.83 | 4.83 |
| 474.63 | 5.29 | 5.29 |
| 502.68 | 6.07 | 6.07 |
| 600.87 | 8.80 | 8.80 |
| 466.53 | 4.47 | 4.47 |
| 433.52 | 4.05 | 4.05 |
| 378.46 | 3.10 | 3.10 |
| 406.51 | 3.88 | 3.88 |
| 420.54 | 4.27 | 4.27 |
| 434.57 | 4.66 | 4.66 |
| 406.51 | 3.73 | 3.73 |
| 420.54 | 4.12 | 4.12 |
| 434.57 | 4.51 | 4.51 |
| 434.57 | 4.51 | 4.51 |
| 420.54 | 4.26 | 4.26 |
| 420.54 | 4.26 | 4.26 |
| 406.51 | 3.87 | 3.87 |
| 432.55 | 4.41 | 4.41 |
| 446.58 | 4.80 | 4.80 |
| 460.60 | 5.19 | 5.19 |
| 418.52 | 4.02 | 4.02 |
| 404.50 | 3.63 | 3.63 |
| 426.50 | 4.60 | 4.60 |
| 444.49 | 4.74 | 4.74 |
| 444.49 | 4.74 | 4.74 |
| 440.53 | 4.91 | 4.91 |
| 476.56 | 5.75 | 5.75 |
| 430.49 | 3.87 | 3.87 |