Basic Information
ID: ALA2390290
Type: Functional
Description: Negative allosteric modulation of rat mGlu2 receptor transfected in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization after 2.5 mins
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2390290
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 335.40 | 2.69 | 2.69 |
| 349.43 | 3.35 | 3.35 |
| 335.40 | 2.69 | 2.69 |
| 335.40 | 2.69 | 2.69 |
| 309.37 | 2.21 | 2.21 |
| 321.38 | 2.30 | 2.30 |
| 321.38 | 2.30 | 2.30 |
| 335.40 | 2.55 | 2.55 |
| 349.43 | 3.08 | 3.08 |
| 359.43 | 3.15 | 3.15 |
| 361.44 | 2.94 | 2.94 |
| 353.39 | 2.83 | 2.83 |
| 353.39 | 2.83 | 2.83 |