Basic Information
ID: ALA2390447
Type: Functional
Description: Binding affinity to CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as dissociation half life at 10 X IC50 preincubated for 1 hr followed by 0.1 nM to 100 uM PGD2 and [35S]-GTPgammaS addition measured after 2 hrs by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA2390447
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.43 | 4.80 | 4.80 |
| 384.46 | 3.01 | 3.01 |
| 446.53 | 4.37 | 4.37 |