Basic Information
ID: ALA2390622
Type: Binding
Description: Antagonist activity at CRTh2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change preincubated for 10 mins followed by PGD2 addition measured after 4 mins by side scatter analysis
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA2390622
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 480.97 | 5.02 | 5.02 |
| 386.43 | 1.99 | 1.99 |
| 384.46 | 3.01 | 3.01 |
| 389.46 | 3.86 | 3.86 |
| 446.53 | 4.37 | 4.37 |