Basic Information
ID: ALA2394384
Type: Binding
Description: Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after 20 mins by spectrophotometric analysis in presence of Bacillus coagulans GST-tagged proline iminopeptidase
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2394384
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 333.82 | 1.61 | 1.61 |
| 290.37 | 3.50 | 3.50 |
| 324.81 | 4.16 | 4.16 |
| 408.81 | 4.44 | 4.44 |
| 308.36 | 3.64 | 3.64 |
| 304.40 | 3.81 | 3.81 |
| 341.87 | 4.84 | 4.84 |
| 310.79 | 4.11 | 4.11 |
| 327.84 | 4.79 | 4.79 |
| 324.81 | 4.14 | 4.14 |
| 234.69 | 2.54 | 2.54 |
| 408.81 | 4.44 | 4.44 |
| 483.33 | 5.65 | 5.65 |
| 524.07 | 2.77 | 2.77 |
| 538.10 | 3.16 | 3.16 |
| 480.02 | 3.07 | 3.07 |
| 494.04 | 3.46 | 3.46 |
| 466.03 | 3.54 | 3.54 |
| 510.09 | 3.24 | 3.24 |
| 480.06 | 3.93 | 3.93 |
| 524.11 | 3.63 | 3.63 |
| 516.07 | 2.48 | 2.48 |
| 560.12 | 2.18 | 2.18 |
| 524.07 | 3.46 | 3.46 |
| 528.49 | 4.11 | 4.11 |
| 524.07 | 3.46 | 3.46 |
| 528.49 | 4.11 | 4.11 |
| 524.07 | 3.46 | 3.46 |
| 512.03 | 3.59 | 3.59 |
| 528.49 | 4.11 | 4.11 |
| 572.94 | 4.22 | 4.22 |
| 539.04 | 3.36 | 3.36 |
| 537.11 | 3.52 | 3.52 |
| 563.15 | 4.06 | 4.06 |
| 524.07 | 3.46 | 3.46 |
| 528.49 | 4.11 | 4.11 |
| 492.41 | 5.67 | 5.67 |
| 506.44 | 6.06 | 6.06 |
| 520.46 | 6.45 | 6.45 |
| 534.49 | 6.84 | 6.84 |
| 548.52 | 7.23 | 7.23 |
| 464.40 | 6.10 | 6.10 |
| 478.43 | 6.14 | 6.14 |
| 492.45 | 6.53 | 6.53 |
| 506.48 | 6.92 | 6.92 |
| 520.51 | 7.31 | 7.31 |
| 534.54 | 7.70 | 7.70 |
| 522.48 | 6.63 | 6.63 |
| 540.93 | 7.57 | 7.57 |
| 531.49 | 6.79 | 6.79 |
| 564.56 | 7.71 | 7.71 |
| 496.44 | 6.51 | 6.51 |
| 512.51 | 6.98 | 6.98 |
| 557.53 | 7.47 | 7.47 |
| 495.46 | 6.18 | 6.18 |
| 463.41 | 6.98 | 6.98 |
| 477.44 | 7.37 | 7.37 |
| 491.47 | 7.76 | 7.76 |
| 505.49 | 8.15 | 8.15 |