Basic Information
ID: ALA2394604
Type: Binding
Description: Inhibition of human recombinant caspase-3 using Ac-DEVD-AMC as substrate assessed as accumulation of AMC preincubated for 10 mins followed by substrate addition measured after 10 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2394604
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.38 | 0.25 | 0.25 |
| 410.49 | 1.44 | 1.44 |
| 428.48 | 1.39 | 1.39 |
| 354.38 | 0.25 | 0.25 |
| 410.49 | 1.44 | 1.44 |
| 428.48 | 1.39 | 1.39 |
| 516.57 | -0.34 | -0.34 |
| 516.57 | -0.34 | -0.34 |
| 572.68 | 0.85 | 0.85 |
| 392.36 | 1.41 | 1.41 |
| 448.46 | 2.60 | 2.60 |
| 466.45 | 2.55 | 2.55 |
| 392.36 | 1.41 | 1.41 |
| 448.46 | 2.60 | 2.60 |
| 466.45 | 2.55 | 2.55 |
| 342.35 | 0.57 | 0.57 |
| 398.46 | 1.76 | 1.76 |
| 342.35 | 0.57 | 0.57 |
| 398.46 | 1.76 | 1.76 |
| 360.34 | 0.87 | 0.87 |
| 416.45 | 2.06 | 2.06 |
| 368.41 | 0.64 | 0.64 |
| 424.52 | 1.83 | 1.83 |
| 442.51 | 1.78 | 1.78 |
| 368.41 | 0.64 | 0.64 |
| 424.52 | 1.83 | 1.83 |
| 442.51 | 1.78 | 1.78 |