Basic Information
ID: ALA2395221
Type: Functional
Description: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNFalpha release at 10 uM incubated for 2 hrs prior to LPS challenge measured after 22 hrs by ELISA relative to LPS-treated control
Organism: Mus musculus
Cell type: RAW264.7
Activity Charts
Bioactivity
Activity Types for Assay ALA2395221
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.33 | 2.37 | 2.37 |
| 328.40 | 3.61 | 3.61 |
| 296.33 | 2.60 | 2.60 |
| 357.23 | 3.22 | 3.22 |
| 312.78 | 3.11 | 3.11 |
| 308.36 | 2.47 | 2.47 |
| 324.36 | 2.17 | 2.17 |
| 324.36 | 2.17 | 2.17 |
| 306.39 | 3.07 | 3.07 |
| 363.44 | 2.29 | 2.29 |
| 317.37 | 2.94 | 2.94 |
| 284.36 | 2.52 | 2.52 |
| 298.39 | 2.83 | 2.83 |
| 401.29 | 3.62 | 3.62 |
| 347.23 | 3.76 | 3.76 |
| 264.74 | 1.03 | 1.03 |
| 315.40 | 0.21 | 0.21 |
| 250.35 | 0.74 | 0.74 |
| 233.30 | -0.29 | -0.29 |
| 483.39 | 3.56 | 3.56 |
| 422.48 | 2.94 | 2.94 |
| 432.55 | 3.42 | 3.42 |
| 489.60 | 2.63 | 2.63 |
| 450.52 | 2.51 | 2.51 |
| 454.55 | 3.95 | 3.95 |
| 424.55 | 3.17 | 3.17 |
| 407.50 | 2.14 | 2.14 |
| 308.16 | 1.46 | 1.46 |
| 289.32 | 0.72 | 0.72 |
| 314.37 | 0.54 | 0.54 |
| 249.32 | 1.07 | 1.07 |
| 268.30 | 1.18 | 1.18 |