Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analysi...

Basic Information

ID: ALA2395921

Type: Binding

Description: Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target: Glutaminyl-peptide cyclotransferase(ALA4508)

Document: ALA2390817

Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA2395921

IC50

Total(42)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
334.45	2.59	2.59
325.44	3.12	3.12
325.44	3.12	3.12
325.44	3.12	3.12
325.44	3.12	3.12
325.44	3.12	3.12
325.44	3.12	3.12
326.43	2.51	2.51
315.40	2.71	2.71
329.43	3.02	3.02
331.47	3.18	3.18
331.47	3.18	3.18
275.38	1.96	1.96
275.38	1.96	1.96
325.44	3.12	3.12
325.44	3.12	3.12
325.44	3.12	3.12
325.44	3.12	3.12
332.43	2.34	2.34
342.47	3.09	3.09
342.47	3.09	3.09
344.48	2.94	2.94
344.48	2.94	2.94
284.32	1.29	1.29
313.43	3.05	3.05
327.46	3.06	3.06
328.45	2.45	2.45
314.42	2.44	2.44
314.42	2.44	2.44
328.45	2.45	2.45
328.45	2.45	2.45
315.40	2.71	2.71
329.43	3.02	3.02
318.40	2.30	2.30
314.46	3.06	3.06
316.43	2.50	2.50
316.43	2.50	2.50
330.46	2.89	2.89
330.46	2.89	2.89
331.45	2.37	2.37
331.45	2.37	2.37
332.43	2.34	2.34