Basic Information
ID: ALA2399371
Type: Binding
Description: Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation after 16 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA2399371
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 473.59 | 6.08 | 6.08 |
| 344.85 | 5.38 | 5.38 |
| 502.77 | 7.28 | 7.28 |
| 320.43 | 5.17 | 5.17 |
| 434.20 | 6.77 | 6.77 |
| 382.89 | 4.89 | 4.89 |
| 327.43 | 5.74 | 5.74 |
| 213.19 | -0.24 | -0.24 |
| 397.76 | 6.52 | 6.52 |
| 606.78 | 8.68 | 8.68 |
| 418.45 | 2.97 | 2.97 |
| 376.58 | 5.51 | 5.51 |
| 384.26 | 3.96 | 3.96 |
| 356.18 | 3.42 | 3.42 |
| 312.45 | 4.64 | 4.64 |
| 776.87 | 4.56 | 4.56 |
| 1736.18 | ||
| 436.08 | 5.56 | 5.56 |
| 346.38 | 5.00 | 5.00 |