Basic Information
ID: ALA2399375
Type: Binding
Description: Agonist activity at PXR (unknown origin) expressed in human HepG2 cells assessed as induction of CYP3A4 transactivation at 40 uM after 16 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA2399375
max activation
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.77 | 7.28 | 7.28 |
| 327.43 | 5.74 | 5.74 |
| 376.58 | 5.51 | 5.51 |
| 384.26 | 3.96 | 3.96 |
| 312.45 | 4.64 | 4.64 |
| 776.87 | 4.56 | 4.56 |
| 436.08 | 5.56 | 5.56 |
| 346.38 | 5.00 | 5.00 |