Inhibition of CYP3A4/5 in human intestinal microsomes using midazolam as substrate after 4 mins

Basic Information

ID: ALA2399576

Type: ADME

Description: Inhibition of CYP3A4/5 in human intestinal microsomes using midazolam as substrate after 4 mins

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Intestine

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 3A4/3A5(ALA2111472)

Document:  ALA2396584

Inhibition of CYP3A4/5 in human intestinal microsomes using midazolam as substrate after 4 mins: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
482.442.362.36
531.444.214.21
482.442.362.36
482.442.362.36
496.472.672.67
496.472.672.67
496.472.672.67
496.472.712.71
482.442.402.40
496.472.712.71
482.440.990.99
496.471.291.29
496.472.672.67
482.442.362.36
482.442.402.40