Basic Information
ID: ALA2399731
Type: Binding
Description: Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carbonate conversion to 6-methoxy-2-naphthaldehyde preincubated for 5 mins prior to substrate addition by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Epoxide hydratase(ALA2409)
Document: ALA2396585
Inhibition of human recombinant soluble epoxide hydrolase assessed as cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxyran-2-yl)methyl] carbonate conversion to 6-methoxy-2-naphthaldehyde preincubated for 5 mins prior to substrate addition by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2399731
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.48 | 3.33 | 3.33 |
| 464.83 | 5.55 | 5.55 |
| 412.53 | 4.34 | 4.34 |
| 381.38 | 2.13 | 2.13 |
| 359.35 | 3.11 | 3.11 |
| 482.82 | 5.69 | 5.69 |
| 420.51 | 4.32 | 4.32 |
| 470.88 | 4.63 | 4.63 |
| 451.45 | 4.46 | 4.46 |
| 425.57 | 4.00 | 4.00 |
| 469.89 | 5.23 | 5.23 |
| 470.88 | 4.63 | 4.63 |
| 484.91 | 4.97 | 4.97 |
| 452.43 | 3.85 | 3.85 |
| 456.85 | 5.57 | 5.57 |
| 469.89 | 5.23 | 5.23 |
| 470.88 | 4.63 | 4.63 |
| 456.85 | 5.57 | 5.57 |
| 438.40 | 4.80 | 4.80 |
| 446.39 | 4.78 | 4.78 |