Assay Report Card

Basic Information

ID: ALA2400274

Type: Binding

Description: Inhibition of Aurora kinase B in human HeLa cells assessed as delay in mitotic arrest by accumulation of multinucleated cells with 4N/8N DNA content at 10 to 1000 nM after 48 hrs by propidium iodide staining-based FACS flow cytometric analysis

Organism: Homo sapiens

Cell type: HeLa

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
464.603.503.50
536.646.136.13